ArticleJournal of feline medicine and surgery2008
Efficacy of amoxycillin and azithromycin for the empirical treatment of shelter cats with suspected bacterial upper respiratory infections.
Article in Journal of feline medicine and surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases.Journal of veterinary internal medicine · 2017Guideline
- Outbreak management of multidrug-resistantJournal of feline medicine and surgery · 2023Article
- Epidemiological Investigation of Feline Upper Respiratory Tract Infection Encourages a Geographically Specific FCV Vaccine.Veterinary sciences · 2023Article
- Occurrence of Antimicrobial Resistance Genes in the Oral Cavity of Cats with Chronic Gingivostomatitis.Animals : an open access journal from MDPI · 2021Article
- Article
- Evaluation of a modified Karnofsky score to assess physical and psychological wellbeing of cats in a hospital setting.Journal of feline medicine and surgery · 2016Article
- Evaluation of intranasal vaccine administration and high-dose interferon- α2b therapy for treatment of chronic upper respiratory tract infections in shelter cats.Journal of feline medicine and surgery · 2016Article
- Feline respiratory disease: what is the role of Mycoplasma species?Journal of feline medicine and surgery · 2014Review
- Descriptive epidemiology of upper respiratory disease and associated risk factors in cats in an animal shelter in coastal western Canada.The Canadian veterinary journal = La revue veterinaire canadienne · 2013Article
- Nasopharyngeal disease in cats: 2. Specific conditions and their management.Journal of feline medicine and surgery · 2012Review
- Snots and snuffles: rational approach to chronic feline upper respiratory syndromes.Journal of feline medicine and surgery · 2010Review
- Treatment of corneal ulcers: what are the medical options?Journal of feline medicine and surgery · 2010Review
- Prevalence of selected infectious organisms and comparison of two anatomic sampling sites in shelter cats with upper respiratory tract disease.Journal of feline medicine and surgery · 2008Article
- Evaluation of pradofloxacin for the treatment of feline rhinitis.Journal of feline medicine and surgery · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty-one cats showing clinical signs of upper respiratory tract disease with a presumed bacterial component based on clinical signs were administered either amoxycillin or azithromycin to determine which drug protocol was optimal for empirical use. A clinical score was determined and nasal and pharyngeal swabs were collected for bacterial culture, virus isolation and polymerase chain reaction prior to the start of therapy. Cats failing to respond to the initial antibiotic were then administered the other drug. There were no differences in clinical scores between the two groups at the start of therapy. Eleven of 31 cats improved after administration of the first antibiotic, 16 cats were switched to the alternate antibiotic, and four cats were removed from the study for additional supportive treatments. Eight of 27 cats failed to respond to either antibiotic. The chi2 test for outcomes revealed no differences in response to therapy for either antimicrobial.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.