ArticleAmerican journal of obstetrics and gynecology2008
Racial differences in C-reactive protein levels during normal pregnancy.
Article in American journal of obstetrics and gynecology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Young Maternal Age on Pregnancy Outcome in Central Europe
Prenatal Inflammation and Perinatal Outcomes
Who cites it
27 citing papers in PubMed.
- The influence of exercise during pregnancy on racial/ethnic health disparities and birth outcomes.BMC pregnancy and childbirth · 2021Trial
- Impact of small-quantity lipid-based nutrient supplement on hemoglobin, iron status and biomarkers of inflammation in pregnant Ghanaian women.Maternal & child nutrition · 2017Trial
- C-reactive protein increases with gestational age during pregnancy among Chinese women.American journal of human biology : the official journal of the Human Biology Council · 2016Trial
- Does C-reactive protein predict recurrent preeclampsia?Hypertension in pregnancy · 2010Trial
- Predictors of upstream inflammation and oxidative stress pathways during early pregnancy.Free radical biology & medicine · 2024Article
- Associations between prenatal maternal stress, maternal inflammation during pregnancy, and children's internalizing and externalizing symptoms throughout childhood.Brain, behavior, and immunity · 2023Article
- Are Pregnant Women Who Are Living with Overweight or Obesity at Greater Risk of Developing Iron Deficiency/Anaemia?Nutrients · 2021Review
- Glucocorticoid receptor sensitivity in early pregnancy in an African American cohort.American journal of reproductive immunology (New York, N.Y. : 1989) · 2020Article
- A Study on the Correlation between C-Reactive Protein Concentration and Teeth with a ≥5 mm Periodontal Pocket in Chronic Periodontitis Patients.International journal of dentistry · 2020Article
- Examination of the role of obesity in the association between childhood trauma and inflammation during pregnancy.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018Article
- Maternal Gut Microbiome Biodiversity in Pregnancy.American journal of perinatology · 2018Article
- Prevalence and Contributors to Low-grade Inflammation in Three U.S. Populations of Reproductive Age Women.Paediatric and perinatal epidemiology · 2018Article
- Reference Intervals for Non-Fasting CVD Lipids and Inflammation Markers in Pregnant Indigenous Australian Women.Healthcare (Basel, Switzerland) · 2017Article
- Partnered sexual activity moderates menstrual cycle-related changes in inflammation markers in healthy women: an exploratory observational study.Fertility and sterility · 2017Observational
- Dietary Inflammatory Potential during Pregnancy Is Associated with Lower Fetal Growth and Breastfeeding Failure: Results from Project Viva.The Journal of nutrition · 2016Observational
- Racial/ethnic differences in self-reported and biologic measures of chronic stress in pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- The aetiology of anaemia during pregnancy: a study to evaluate the contribution of iron deficiency and common infections in pregnant Ugandan women.Public health nutrition · 2015Article
- Effects of maternal inflammation and exposure to cigarette smoke on birth weight and delivery of preterm babies in a cohort of indigenous Australian women.Frontiers in immunology · 2015Article
- First-trimester maternal serum C-reactive protein as a predictor of third-trimester impaired glucose tolerance.Reproductive sciences (Thousand Oaks, Calif.) · 2015Article
- Positive maternal C-reactive protein predicts neonatal sepsis.Yonsei medical journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveThe purpose of this study was to characterize serum C-reactive protein (CRP) levels in a diverse population of healthy pregnant women with the use of a high sensitivity assay. STUDY
designWe conducted a cross-sectional analysis of a cohort of 775 pregnant women. CRP was measured on serum specimens that were drawn at < 26 weeks of gestation with highly sensitive enzyme-linked immunosorbent assay kits.
resultsMedian CRP was 4.8 mg/L (interquartile range, 0.63-15.7). Black women had higher median CRP values than did white women (7.68 vs 2.59 mg/L; P < .001). Black women demonstrated higher levels of CRP, even after the data were controlled for known confounding factors such as smoking and maternal weight.
conclusionPregnancy is an inflammatory stressor. The cause of racial differences is unclear but may be important for understanding racial disparities in the incidence of inflammatory disorders such as preterm labor and preeclampsia.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.