ReviewHuman reproduction update
Cytogenetic determinants of male fertility.
Review in Human reproduction update. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
55 citing papers in PubMed, 179 citations in OpenAlex.
- Genetic and epigenetic insights into non-obstructive azoospermia: mechanisms, biomarkers, and clinical perspectives.Reproductive biology and endocrinology : RB&E · 2025Review
- Article
- Chromosomal Roadblocks in Male Fertility: Mechanisms, Risk Factors and Syndromes.Medicina (Kaunas, Lithuania) · 2025Review
- Refining the genetic diagnostic puzzle: A case report on a Chinese ARPKD patient with a reciprocal balanced translocation and c.2507 T > C (p.V836A) in PKHD1.Nephrology (Carlton, Vic.) · 2024Article
- Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells.Reproductive biology and endocrinology : RB&E · 2023Article
- Sperm Meiotic Segregation Analysis of Reciprocal Translocations Carriers: We Have Bigger FISH to Fry.International journal of molecular sciences · 2023Review
- Hypothalamic-Pituitary-Gonadal Axis Disorders Impacting Fertility in Both Sexes and the Potential of Kisspeptin-Based Therapies to Treat Them.Handbook of experimental pharmacology · 2023Review
- Candidate genes for infertility: an in-silico study based on cytogenetic analysis.BMC medical genomics · 2022Article
- Update on genetic screening and treatment for infertile men with genetic disorders in the era of assisted reproductive technology.Clinical and experimental reproductive medicine · 2021Article
- Article
- Therapeutic Dose of Hydroxyurea-Induced Synaptic Abnormalities on the Mouse Spermatocyte.Frontiers in physiology · 2021Article
- Chromosome Abnormalities Related to Reproductive and Sexual Development Disorders: A 5-Year Retrospective Study.BioMed research international · 2021Article
- Nonsurgical Management of Oligozoospermia.The Journal of clinical endocrinology and metabolism · 2020Article
- High rates of aneuploidy, mosaicism and abnormal morphokinetic development in cases with low sperm concentration.Journal of assisted reproduction and genetics · 2020Article
- Obstetric and perinatal outcomes of intracytoplasmic sperm injection for infertile men with Y chromosome microdeletions.Medicine · 2019Article
- Developmental retardation due to paternal 5q/11q translocation in a Chinese infant: clinical, chromosomal and microarray characterization.Journal of genetics · 2019Article
- Chromosomal rearrangements as a source of new gene formation in Drosophila yakuba.PLoS genetics · 2019Article
- Chromosomal scan of single sperm cells by combining fluorescence-activated cell sorting and next-generation sequencing.Journal of assisted reproduction and genetics · 2019Article
- 46 XX male syndrome with hypogonadotropic hypogonadism: A case report.Northern clinics of Istanbul · 2019Article
- Analysis of meiotic segregation modes in biopsied blastocysts from preimplantation genetic testing cycles of reciprocal translocations.Molecular cytogenetics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCytogenetic abnormalities have been known to be important causes of male infertility for decades.
methodsResearch publications from 1978 to 2008, from PubMed, have been reviewed.
resultsThese studies have greatly improved our information on somatic chromosomal abnormalities such as translocations, inversions and sex chromosomal anomalies, and their consequences to the cytogenetic make-up of human sperm. Also, we have learned that infertile men with a normal somatic karyotype have an increased risk of chromosomally abnormal sperm and children. New techniques such as single sperm typing and synaptonemal complex analysis have provided valuable insight into the association between meiotic recombination and the production of aneuploid sperm. These meiotic studies have also unveiled errors of chromosome pairing and synapsis, which are more common in infertile men.
conclusionsThese studies allow us to provide more precise information to infertile patients, and further our basic knowledge in the causes of male infertility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.