ArticleChemical senses2008
Sniffing behavior of mice during performance in odor-guided tasks.
Article in Chemical senses, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
149 citing papers in PubMed.
- In-dwelling microfluidic device for precise and reliable intranasal drug delivery during freely moving behavior.Lab animal · 2026Article
- Dexterous single sniffs for ethological active olfaction.Science advances · 2026Article
- An olfactory-prefrontal cortical circuit supports social recognition.Research square · 2026Article
- Respiratory pauses highlight sleep architecture in mice.Nature communications · 2026Article
- Article
- Odor identity decoding by mitral/tufted cells in the olfactory bulb from large-scale pooled datasets.iScience · 2026Article
- Fat sensory cues in early life program central response to food and obesity.Nature metabolism · 2025Article
- Reflex regulation of respiration and heart rate by inhaled activators of vagal bronchopulmonary afferents.Journal of neurophysiology · 2025Article
- Breathing Rate as a Marker for Noise-Induced Stress in Guinea Pigs.Brain sciences · 2025Article
- Mouse olfactory system acts as anemo-detector and anemo-discriminator.Science advances · 2025Article
- Odor Experience Stabilizes Glomerular Output Representations in Two Mouse Models of Autism.eNeuro · 2025Article
- Global coordination of brain activity by the breathing cycle.Nature reviews. Neuroscience · 2025Review
- Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Design Principles From Natural Olfaction for Electronic Noses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Autistic behavior is a common outcome of biallelic disruption of PDZD8 in humans and mice.Molecular autism · 2025Article
- Rhythm Facilitates Auditory Working Memory via Beta-Band Encoding and Theta-Band Maintenance.Neuroscience bulletin · 2025Article
- Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb.Chemical senses · 2025Article
- Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior.Nature communications · 2025Article
- Characterization of an olfactory system dysfunction model: a vanadium dose-effect study via nose-to-brain delivery in rats.Frontiers in neuroanatomy · 2025Article
- Oscillations in the prefrontal-hippocampal circuit couple to respiration-related oscillations during all phases of a working memory task.Frontiers in behavioral neuroscience · 2025Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on byWhy sniff?2008
Authors and funding
4 authors.
Funding
Abstract
Sniffing, a rhythmic inhalation and exhalation of air through the nose, is a behavior thought to play a critical role in shaping how odor information is represented and processed by the nervous system. Although the mouse has become a prominent model for studying olfaction, little is known about sniffing behavior in mice. Here, we characterized mouse sniffing behavior by measuring intranasal pressure transients in behaving mice. Sniffing was monitored during unstructured exploratory behavior and during performance of 3 commonly used olfactory paradigms: a habituation/dishabituation task, a sand digging-based discrimination task, and a nose poke-based discrimination task. We found that respiration frequencies in quiescent mice ranged from 3 to 5 Hz--higher than that reported for rats. During exploration, sniff frequency increased up to approximately 12 Hz and was highly dynamic, with rapid changes in frequency, amplitude, and waveform. Sniffing behavior varied strongly between tasks as well as for different behavioral epochs of each task. For example, mice performing the digging-based task showed little increase in sniff frequency prior to digging, whereas mice performing a nose poke-based task showed robust increases. Mice showed large increases in sniff frequency prior to reward delivery in all tasks. Mice also showed increases in sniff frequency when nose poking in a nonodor-guided task. These results show that mouse sniffing behavior is highly dynamic, varies with behavioral context, and is strongly modulated by olfactory as well as nonolfactory events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.