ArticleJournal of the Royal Society, Interface2008
Lab-on-a-chip technologies for proteomic analysis from isolated cells.
Article in Journal of the Royal Society, Interface, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 69 citations in OpenAlex.
- Microfluidic Electroporation: Recent Advances and Applications.Advances in experimental medicine and biology · 2026Review
- Bacterial Proteomics and Antibiotic Resistance Identification: Is Single-Cell Analysis a Worthwhile Pursuit?Pathogens (Basel, Switzerland) · 2025Review
- Advances in bioinspired polymer hydrogel systems with biomedical functionalities.Science and technology of advanced materials · 2025Review
- Laser Machined Fiber-based Microprobe: Application in Microscale Electroporation.Advanced fiber materials · 2022Article
- A Microfluidic System of Gene Transfer by Ultrasound.Micromachines · 2022Article
- Recent Advances in Microscale Electroporation.Chemical reviews · 2022Review
- Review of Microfluidic Methods for Cellular Lysis.Micromachines · 2021Review
- Electrochemical cell lysis of gram-positive and gram-negative bacteria: DNA extraction from environmental water samples.Electrochimica acta · 2020Article
- Active particles as mobile microelectrodes for selective bacteria electroporation and transport.Science advances · 2020Article
- Simultaneous electroporation and dielectrophoresis in non-electrolytic micro/nano-electroporation.Scientific reports · 2018Article
- Numerical modeling of bi-polar (AC) pulse electroporation of single cell in microchannel to create nanopores on its membrane.The Journal of membrane biology · 2014Article
- Microfluidic electroporation for cellular analysis and delivery.Lab on a chip · 2013Review
- Article
- Multiplexed protein analysis using encoded antibody-conjugated microbeads.Journal of the Royal Society, Interface · 2011Article
- Electroporation and lysis of marine microalga Karenia brevis for RNA extraction and amplification.Journal of the Royal Society, Interface · 2011Article
- Microfluidic Device for Capture and Isolation of Single Cells.Proceedings of SPIE--the International Society for Optical Engineering · 2010Article
- Microscale electroporation: challenges and perspectives for clinical applications.Integrative biology : quantitative biosciences from nano to macro · 2009Review
- New frontiers in single-cell analysis.Journal of the Royal Society, Interface · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Lab-on-a-chip systems offer a versatile environment in which low numbers of cells and molecules can be manipulated, captured, detected and analysed. We describe here a microfluidic device that allows the isolation, electroporation and lysis of single cells. A431 human epithelial carcinoma cells, expressing a green fluorescent protein-labelled actin, were trapped by dielectrophoresis within an integrated lab-on-a-chip device containing saw-tooth microelectrodes. Using these same trapping electrodes, on-chip electroporation was performed, resulting in cell lysis. Protein release was monitored by confocal fluorescence microscopy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.