Evidence map›Paper›PMID 18534842›Full record

ReviewCurrent opinion in structural biology2008

Histone chaperones in nucleosome eviction and histone exchange.

Young-Jun Park, Karolin Luger

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 188 citations in OpenAlex.

  1. Review
  2. Acetylation of Histone H3 in Cancer Progression and Prognosis.International journal of molecular sciences · 2024
    Review
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  12. Review
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  14. Review
  15. Article
  16. Structure and function of the histone chaperone FACT - Resolving FACTual issues.Biochimica et biophysica acta. Gene regulatory mechanisms · 2018
    Review
  17. Article
  18. Article
  19. Review
  20. Article

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Young-Jun ParkHoward Hughes Medical Institute and Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523-1870, United States. yipark@lamar.colostate.edu
Karolin Luger
Colorado State University · USHoward Hughes Medical Institute · US

Funding

Structure and Function of Nucleosome Assembly Protein 1R01GM067777 · NIGMS · UNIVERSITY OF COLORADO · PI LUGER, KAROLIN · 2003 to 2015
$3.7M
Structure of nucleosomes in complex with transcriptional regulatorsR01GM061909 · NIGMS · COLORADO STATE UNIVERSITY-FORT COLLINS · PI LUGER, KAROLIN · 2000 to 2009
$2.0M
Howard Hughes Medical InstituteNIGMS NIH HHS GM061909NIGMS NIH HHS GM067777NIGMS NIH HHS R01 GM061909NIGMS NIH HHS R01 GM067777
6 · The paper itself

Abstract

The recent two years have led to the realization that histone chaperones contribute to the delicate balance between nucleosome assembly and re-assembly during transcription, and may in fact be involved as much in histone eviction as they are in chromatin assembly. Recent structural studies (in particular, the structure of an Asf1-H3/H4 complex) have suggested mechanisms by which this may be accomplished. The incorporation of various histone variants into nucleosomes has diverse effects on nucleosome structure, stability, and the ability of nucleosomal arrays to condense into chromatin higher order structures. It is likely that these seemingly independent ways to modify chromatin structure are interdependent.

Indexed as

HistonesModels, MolecularMolecular ChaperonesHistonesMolecular Chaperones

Identifiers

PMID18534842
PMCPMC2525571
OpenAlexW1999011979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.