Evidence map›Paper›PMID 18534094›Full record

ReviewJournal of biomaterials science. Polymer edition2008

Diagnostic devices as biomaterials: a review of nucleic acid and protein microarray surface performance issues.

Peng Wu, David G Castner, David W Grainger

Abstract readReview
In one paragraph

Review in Journal of biomaterials science. Polymer edition, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
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  7. Review
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  15. Article
  16. Thermostable DNA immobilization and temperature effects on surface hybridization.Langmuir : the ACS journal of surfaces and colloids · 2012
    Article
  17. Article
  18. Probing Albumin Adsorption onto Calcium Phosphates by XPS and ToF-SIMS.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2011
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Peng WuDepartment of Chemistry, University of Alberta, Edmonton, AB, Canada T6G 2G2.
David G Castner
David W Grainger
University of Alberta · CAUniversity of Utah · USUniversity of Washington · US

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G · 2003 to 2019
$17.6M
DNA Microarray Surface Analysis to Optimize DetectionR01EB001473 · NIBIB · UNIVERSITY OF UTAH · PI GRAINGER, DAVID W · 2003 to 2011
$2.8M
Multianalyte physiological optical waveguide sensingR01EB000726 · NIBIB · COLORADO STATE UNIVERSITY-FORT COLLINS · PI DANDY, DAVID S · 2002 to 2005
$2.3M
NIBIB NIH HHS EB001473NIBIB NIH HHS EB002027NIBIB NIH HHS EB00726NIBIB NIH HHS P41 EB002027NIBIB NIH HHS R01 EB000726NIBIB NIH HHS R01 EB001473
6 · The paper itself

Abstract

This review of current DNA and protein microarray diagnostic and bio-analytical technologies focuses on the different surface chemistries used in these miniaturized surface-capture formats. Description of current strategies in bio-immobilization and coupling to create multiplexed affinity bioassays in micrometer-sized printed spots, problems with current formats and review of some detection methods are included. Recommendations for improving long-standing challenges in DNA- and protein-based arrays are forwarded. The biomaterials community can contribute relevant expertise to these formidable bio-interfacial problems that represent significant barriers to clinical implementation of microarray assays.

Indexed as

Molecular Diagnostic TechniquesOligonucleotide Array Sequence AnalysisProtein Array Analysis

Identifiers

PMID18534094
PMCPMC13635952
OpenAlexW1998490971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.