ReviewThe journal of spinal cord medicine2008
Effects of spinal cord injury on semen parameters.
Review in The journal of spinal cord medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 77 citations in OpenAlex.
- Spinal Cord Injury-Related Male Infertility: Oxidative Stress, Inflammation, and Sperm DNA Damage.Journal of clinical medicine · 2026Review
- Sexual Dysfunction and Infertility in Male Patients With Spinal Cord Injury: A Narrative Review.Cureus · 2026Review
- Spinal cord injury and male infertility: Effect of the inflammasome proteins on semen quality.The journal of spinal cord medicine · 2025Article
- Effects of Melissa officinalis extract in the expression of NLRP3 gene in testicular tissue and sperm parameters in the male rat model of spinal cord injury.Journal of molecular histology · 2025Article
- Letter to the Editor Re: Low-frequency bladder vibration for the treatment of urinary tract infections in spinal cord injury patients with neurogenic bladder by Zhang et al.International urology and nephrology · 2025Article
- Consequences of spinal cord injury on the sympathetic nervous system.Frontiers in cellular neuroscience · 2023Review
- Free circulating DNA and DNase activity in the ejaculates of men with spinal cord injury.Spinal cord · 2021Article
- Successful conception using home intravaginal insemination following spinal cord injury in a man.Canadian family physician Medecin de famille canadien · 2020Article
- The incidence and etiology of sperm DNA fragmentation in the ejaculates of males with spinal cord injuries.Spinal cord · 2020Article
- Testosterone Reduces Spinal Cord Injury-Induced Effects on Male Reproduction by Preventing CADM1 Defect.Cell journal · 2018Article
- Lipid Peroxidation and Its Role in the Expression of NLRP1a and NLRP3 Genes in Testicular Tissue of Male Rats: a Model of Spinal Cord InjuryIranian biomedical journal · 2018Article
- Improvement of Sexual and Reproductive Function in Men with Spinal Cord Lesion.Acta clinica Croatica · 2018Review
- The etiologies of DNA abnormalities in male infertility: An assessment and review.International journal of reproductive biomedicine · 2017Review
- Sperm chromatin condensation, DNA integrity, and apoptosis in men with spinal cord injury.The journal of spinal cord medicine · 2013Article
- Outcomes with intracytoplasmic sperm injection of cryopreserved sperm from men with spinal cord injury.Basic and clinical andrology · 2013Article
- Sperm chromosomal aneuploidy and DNA integrity of infertile men with anejaculation.Journal of assisted reproduction and genetics · 2012Article
- Infertility in men with spinal cord injury: research and treatment.Scientifica · 2012Review
- Select spinal lesions reveal multiple ascending pathways in the rat conveying input from the male genitalia.The Journal of physiology · 2010Article
- Treatment of infertility in men with spinal cord injury.Nature reviews. Urology · 2010Review
- Advances in the management of infertility in men with spinal cord injury.Asian journal of andrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
OBJECTIVE/
backgroundNeurogenic reproductive dysfunction in men with spinal cord injury (SCI) is common and the result of a combination of impotence, ejaculatory failure, and abnormal semen characteristics. It is well established that the semen quality of men with SCI is poor and that changes are seen as early as 2 weeks after injury. The distinguishing characters of poor quality are abnormal sperm motility and viability. In the majority of the men with SCI, the sperm count is not abnormal. We elaborate on the effects of the SCI on semen parameters that may contribute to poor motility and poor viability.
methodsReview.
designPubMed and MEDLINE databases were searched using the following key words: spinal cord injuries, fertility, sexual dysfunction, and spermatogenesis. All literature was reviewed by the team of authors according to the various stages of sperm development and transport in the male reproductive cycle.
findingsThe cause of asthenozoospermia appears to be multifactorial.
conclusionCurrent literature does not support the preeminence of a single factor relating to neurogenic reproductive dysfunction in men with SCI. After SCI, there is ample evidence of disturbance of sperm production, maturation and storage, and transport due to an abnormal neuroendocrine milieu. Semen quality seems to be primarily affected by changes to the seminal plasma constituents, type of bladder management, and the neurogenic impairment to the ejaculatory function. Further focused and structured studies are required.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.