SynthesisRadiation and environmental biophysics2008
Are pre- or postnatal diagnostic X-rays a risk factor for childhood cancer? A systematic review.
Synthesis in Radiation and environmental biophysics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.Pediatric radiology · 2021Pooled it
- Visual Assessment of Rib Cartilage Mineralization in Thoracic Radiographs as an Indicator of Age in Juvenile Dogs of Various Breeds.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026Article
- Infantile neuroblastoma and maternal occupational exposure to medical agents.Pediatric research · 2025Article
- Review
- Article
- Inheritance of paternal lifestyles and exposures through sperm DNA methylation.Nature reviews. Urology · 2023Review
- Lung ultrasonography decreases radiation exposure in newborns with respiratory distress: a retrospective cohort study.European journal of pediatrics · 2022Article
- Effects of Lifestyle and Environmental Factors on the Risk of Acute Myeloid Leukemia: Result of a Hospital-based Case-Control Study.Journal of research in health sciences · 2021Article
- Long-term follow-up after fetal radiation exposure during endoscopic retrograde cholangiopancreatography.Endoscopy international open · 2020Article
- Neonatal respiratory distress syndrome: Chest X-ray or lung ultrasound? A systematic review.Ultrasound (Leeds, England) · 2017Review
- In utero exposure to radiation and haematological malignancies: pooled analysis of Southern Urals cohorts.British journal of cancer · 2017Article
- Evaluation of radiation exposure dose at double-balloon endoscopy for the patients with small bowel disease.Nagoya journal of medical science · 2016Article
- Risk of solid cancer in the offspring of female workers of the Mayak nuclear facility in the Southern Urals, Russian Federation.Radiation and environmental biophysics · 2016Article
- Chemotherapeutic treatment of colorectal cancer in pregnancy: case report.Journal of medical case reports · 2015Article
- Infrared thermography is useful for ruling out fractures in paediatric emergencies.European journal of pediatrics · 2015Article
- Predicted cancer risks induced by computed tomography examinations during childhood, by a quantitative risk assessment approach.Radiation and environmental biophysics · 2014Article
- Risk of cancer associated with cardiac catheterization procedures during childhood: a cohort study in France.BMC public health · 2013Article
- Cancer mortality following in utero exposure among offspring of female Mayak Worker Cohort members.Radiation research · 2012Article
- Bone age assessment by dual-energy X-ray absorptiometry in children: an alternative for X-ray?The British journal of radiology · 2012Article
- Radiation exposure from CT in early childhood: a French large-scale multicentre study.The British journal of radiology · 2012Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The risk of cancer after diagnostic X-rays received as fetus or during early childhood has been investigated in many studies. The results of recent epidemiological studies are summarized in a present systematic review. The strategies for literature search, inclusion criteria, and items for study quality assessment were defined in the study protocol. All epidemiological case control and cohort studies published in English between 1990 and 2006 that reported at least the size of the study population and risk estimates were included. Results were summarized separately for pre- and postnatal exposure and for each cancer site. Nineteen case control studies and six cohort studies matched the inclusion criteria. No association of leukemia with prenatal exposures was observed in nine case control studies. Heterogeneous results were found for postnatal exposures and leukemia in four studies. No significant effect of pre- and postnatal X-ray exposure was observed for other cancer sites (non-Hodgkin lymphomas, solid tumors and brain tumors). Most studies have limitations in study design, study size, or exposure measurement, and involve very low exposures. These results thus do not contradict previous evidence accumulated since 1956 indicating risk increases associated with prenatal X-ray exposure. Computed tomography is not covered in the studies and needs to be investigated in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.