ArticleNucleic acids research1991
Identification of nuclear factor delta EF1 and its binding site essential for lens-specific activity of the delta 1-crystallin enhancer.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Role of ZEB1 in angiogenesis and therapeutic potential (Review).International journal of molecular medicine · 2026Review
- Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration.Cytokine & growth factor reviews · 2025Review
- Article
- Regulation of ZEB1 Function and Molecular Associations in Tumor Progression and Metastasis.Cancers · 2022Review
- Oncogenic functions of ZEB1 in pediatric solid cancers: interplays with microRNAs and long noncoding RNAs.Molecular and cellular biochemistry · 2021Review
- Review
- Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells.International journal of molecular sciences · 2020Article
- Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer.Journal of translational medicine · 2020Review
- Transforming growth factor β1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of δEF1.The FEBS journal · 2016Article
- Article
- δEF1 upregulates CDK4 transcription via the E2-box element on the CDK4 promoter.Experimental and therapeutic medicine · 2014Article
- A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- δEF1 down-regulates ER-α expression and confers tamoxifen resistance in breast cancer.PloS one · 2012Article
- CD13/APN transcription is regulated by the proto-oncogene c-Maf via an atypical response element.Gene · 2007Article
- BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells.BMC cancer · 2007Article
- The 5'-AT-rich half-site of Maf recognition element: a functional target for bZIP transcription factor Maf.Nucleic acids research · 2005Article
- The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation.Molecular and cellular biology · 2001Article
- Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1.Molecular and cellular biology · 1999Article
- Impairment of T cell development in deltaEF1 mutant mice.The Journal of experimental medicine · 1997Article
- Involvement of SOX proteins in lens-specific activation of crystallin genes.The EMBO journal · 1995Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lens-specific reglatory element of the delta 1-crystallin enhancer lies within the core segment (Goto et al., (1990) Mol. Cell. Biol. 10, 935-964). The element was allocated within the 55 bp long HN fragment of the core. Block-wise base substitutions were introduced to the 55 bp and their effect on the enhancer activity of the multimers in lens cells was examined. By base sequence alteration of either of the contiguous blocks 5 and 6, with their original sequence of TTGCT and CACCT, respectively, enhancer activity was totally lost. A lens nuclear factor delta EF1 was found which bound specifically to the base sequences defined by the blocks. DNA binding activity very similar to delta EF1 was also found in extracts of tissues other than lens, suggesting that delta EF1 participates in lens-specific regulation through tissue-dependent modification or interaction with other factors.
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