ArticleAJNR. American journal of neuroradiology2008
No increased risk for contrast-induced nephropathy after multiple CT perfusion studies of the brain with a nonionic, dimeric, iso-osmolal contrast medium.
Article in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Clinical and experimental nephrology · 2020Guideline
- Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version. JSN, JRS, and JCS Joint Working Group.Japanese journal of radiology · 2013Guideline
- Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version : JSN, JRS, and JCS Joint Working Group.Clinical and experimental nephrology · 2013Guideline
- Comparison of changes in creatinine clearance in patients undergoing optical coherence tomography versus intravascular ultrasound.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Incidence of acute kidney injury in patients with acute ischaemic stroke undergoing CT angiography (CTA) and CT perfusion (CTP): a systematic review and meta-analysis.BMJ neurology open · 2024Article
- Renal Safety of Repeated Intravascular Administrations of Iodinated or Gadolinium-Based Contrast Media within a Short Interval.Korean journal of radiology · 2021Article
- Updated guidelines for intravenous contrast use for CT and MRI.Emergency radiology · 2020Review
- Save the Brain First: CTA and Mechanical Thrombectomy in Patients at Risk for Contrast-Induced Nephropathy.AJNR. American journal of neuroradiology · 2020Article
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Japanese journal of radiology · 2020Article
- Contrast CT Scans in the Emergency Department Do Not Increase Risk of Adverse Renal Outcomes.The western journal of emergency medicine · 2016Article
- Individually tailored contrast enhancement in CT pulmonary angiography.The British journal of radiology · 2016Article
- Optimized imaging of the midface and orbits.GMS current topics in otorhinolaryngology, head and neck surgery · 2015Review
- The cost-utility of CT angiography and conventional angiography for people presenting with intracerebral hemorrhage.PloS one · 2014Article
- Article
- Development of contrast-induced nephropathy in subarachnoid hemorrhage: a single center perspective.Neurocritical care · 2013Article
- Letter to the Editor re: Are intravenous injections of contrast media really less nephrotoxic than intra-arterial injections?European radiology · 2013Article
- Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material.Radiology · 2013Article
- Article
- Contrast-induced nephropathy in patients with renal insufficiency undergoing contrast-enhanced MDCT.European radiology · 2012Article
- Functional contrast-enhanced CT for evaluation of acute ischemic stroke does not increase the risk of contrast-induced nephropathy.AJNR. American journal of neuroradiology · 2010Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeContrast-induced nephropathy (CIN) is one of the most common causes of in-hospital acute renal failure. The aim of this study was to assess the risk for CIN after repeated administration of the nonionic, dimeric, iso-osmolal contrast agent iodixanol regardless of pre-existing renal function. Changes in serum creatinine (SCr) levels were compared with those of control subjects who did not receive iodinated contrast media (CM). MATERIALS AND
methodsBetween January 2005 and March 2007, a total of 100 consecutive patients were prospectively included. Patients underwent a CT perfusion (CTP) study of the brain from clinical signs of acute cerebral infarction. CTP was performed with an intravenous bolus of 60 mL of iodixanol-270. Precontrast and postcontrast SCr levels were obtained, and the CTP study was repeated within 32 hours and postcontrast SCR was assessed. The control group consisted of 100 patients scheduled for plain cranial CT examination, who were not exposed to iodinated CM.
resultsMean baseline SCr level was 0.96 +/- 0.35 mg/dL in the contrast group and 1.14 +/- 0.74 mg/dL in the control group. After repeated administration of CM, a total of 7 patients had a relative increase of greater than or equal to 25% compared with baseline. In the control group, a relative increase of 25% or more was seen in 12 patients. The difference in the incidence of the rise in SCr of >25% was not significantly different (P = .094).
conclusionMultiple contrast-enhanced studies with intravenously administered iodixanol are not associated with a higher risk for CIN compared with a control group receiving no CM.
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