Evidence map›Paper›PMID 18524948›Full record

ReviewEndocrine-related cancer2008

Integrins in prostate cancer progression.

Hira Lal Goel, Jing Li, Sophia Kogan, Lucia R Languino

Open access · bronzeAbstract readReview
In one paragraph

Review in Endocrine-related cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 178 citations in OpenAlex.

  1. Article
  2. Article
  3. Anoikis: To Die or Not to Die?International journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Microfluidic-based human prostate-cancer-on-chip.Frontiers in bioengineering and biotechnology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hira Lal GoelDepartment of Cancer Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Jing Li
Sophia Kogan
Lucia R Languino
University of Massachusetts Chan Medical School · US

Funding

INTEGRIN SIGNALING PATHWAYS IN PROSTATE CANCERR01CA089720 · NCI · YALE UNIVERSITY · PI LANGUINO, LUCIA R. · 2001 to 2014
$2.8M
Beta1 Integrins and IGF-l Receptor in Prostate CancerR01CA109874 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LANGUINO, LUCIA R. · 2005 to 2015
$2.7M
NCI NIH HHS R01 CA089720NCI NIH HHS R01 CA-109874NCI NIH HHS R01 CA109874NCI NIH HHS R01 CA-89720
6 · The paper itself

Abstract

Integrins, which are transmembrane receptors for extracellular matrix proteins, play a key role in cell survival, proliferation, migration, gene expression, and activation of growth factor receptors. Their functions and expression are deregulated in several types of cancer, including prostate cancer. In this article, we review the role of integrins in prostate cancer progression and their potential as therapeutic targets.

Indexed as

AnimalsAntineoplastic AgentsClinical Trials as TopicDisease ProgressionGene Expression Regulation, NeoplasticHumansIntegrinsMaleNeoplasm MetastasisNeovascularization, PathologicProstatic NeoplasmsTumor BurdenAntineoplastic AgentsIntegrins

Identifiers

PMID18524948
PMCPMC2668544
OpenAlexW2128005590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.