Evidence map›Paper›PMID 18523771›Full record

ReviewCancer immunology, immunotherapy : CII2008

Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines.

Tanja D de Gruijl, Alfons J M van den Eertwegh, Herbert M Pinedo, Rik J Scheper

Abstract readReview
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
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  7. Cancer Vaccines: A Novel Revolutionized Approach to Cancer Therapy.Indian journal of clinical biochemistry : IJCB · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Leveraging T cells for cancer immunotherapy.Immunity & inflammation · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanja D de GruijlDepartment of Medical Oncology, Vrije Universiteit medical Center, Amsterdam, The Netherlands.
Alfons J M van den Eertwegh
Herbert M Pinedo
Rik J Scheper

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of tumor vaccination is currently undergoing a shift in focus, from individualized tailor-made vaccines to more generally applicable vaccine formulations. Although primarily predicated by financial and logistic considerations, stemming from a growing awareness that clinical development for wide-scale application can only be achieved through backing from major pharmaceutical companies, these new approaches are also supported by a growing knowledge of the intricacies and minutiae of antigen presentation and effector T-cell activation. Here, the development of whole-cell tumor and dendritic cell (DC)-based vaccines from an individualized autologous set-up to a more widely applicable allogeneic approach will be discussed as reflected by translational studies carried out over the past two decades at our laboratories and clinics in the vrije universiteit medical center (VUmc) in Amsterdam, The Netherlands.

Indexed as

Cancer VaccinesClinical Trials as TopicDendritic CellsHumansImmunotherapy, AdoptiveNeoplasmsTransplantation, AutologousTransplantation, HomologousCancer Vaccines

Identifiers

PMID18523771
PMCPMC2491427

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.