ArticleJournal of exposure science & environmental epidemiology2009
Levels of urinary total and speciated arsenic in the US population: National Health and Nutrition Examination Survey 2003-2004.
Article in Journal of exposure science & environmental epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.
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Who cites it
75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Potential Co-exposure to Arsenic and Fluoride and Biomonitoring Equivalents for Mexican Children.Annals of global health · 2018Pooled it
- Arsenic Exposure and Predicted 10-Year Atherosclerotic Cardiovascular Risk Using the Pooled Cohort Equations in U.S. Hypertensive Adults.International journal of environmental research and public health · 2016Pooled it
- Arsenic species and lipid metabolism under low-to-moderate arsenic exposure: evidence from NHANES and a Chinese adult population.Frontiers in endocrinology · 2026Article
- Association between urinary arsenic concentration and genetic polymorphisms in Korean adults.Toxicological research · 2024Article
- Association between urinary arsenic and hearing threshold shifts in adults in the United States, National Health and Nutrition Examination Survey, 2015-2016.Frontiers in public health · 2024Article
- Exposure to Arsenic and Subclinical Cardiovascular Disease in 9- to 11-Year-Old Children, Syracuse, New York.JAMA network open · 2023Article
- Biomonitoring California Protocol for Following up on Elevated Levels of Urinary Arsenic.International journal of environmental research and public health · 2023Article
- Protective efficacy ofToxicological research · 2022Article
- Article
- Exposure to arsenolipids and inorganic arsenic from marine-sourced dietary supplements.Chemosphere · 2022Article
- Biological monitoring and health assessment of 21 metal(loid)s in children and adolescents in Liuzhou City, Southwest China.Environmental science and pollution research international · 2022Article
- Environmental exposure to metals and the risk of high blood pressure: a cross-sectional study from NHANES 2015-2016.Environmental science and pollution research international · 2022Article
- Association of urinary arsenic and sleep disorder in the US population: NHANES 2015-2016.Environmental science and pollution research international · 2022Article
- Exposure to Nicotine and Toxicants Among Dual Users of Tobacco Cigarettes and E-Cigarettes: Population Assessment of Tobacco and Health (PATH) Study, 2013-2014.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Article
- Development and validation of a biomonitoring method to measure As, Cr, and Ni in human urine samples by ICP-UCT-MS.International journal of hygiene and environmental health · 2021Article
- Urinary total arsenic and arsenic methylation capacity in pregnancy and gestational diabetes mellitus: A case-control study.Chemosphere · 2021Article
- Demographic predictors of urinary arsenic in a low-income predominantly Hispanic pregnancy cohort in Los Angeles.Journal of exposure science & environmental epidemiology · 2021Article
- Biomarkers of Exposure among USA Adult Hookah Users: Results from Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study (2013-2014).International journal of environmental research and public health · 2020Article
- Temporal trend of arsenic in outdoor air PMEnvironmental science and pollution research international · 2020Article
- Urinary speciated arsenic and depression among US adults.Environmental science and pollution research international · 2020Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo provide levels of total and speciated urinary arsenic in a representative sample of the US population.
methodsFor the first time, total arsenic and seven inorganic and organic arsenic species were measured in the urine of participants (n=2557) for the 2003-2004 National Health and Nutrition Examination Survey (NHANES). Data were compiled as geometric means and selected percentiles of urinary arsenic concentrations (microg/l) and creatinine-corrected urinary arsenic (microg/g creatinine) for total arsenic, dimethylarsinic acid, arsenobetaine, and a sum of the inorganic related species.
resultsArsenic acid, arsenous acid, arsenocholine, and trimethylarsine oxide were detected in 7.6%, 4.6%, 1.8%, and 0.3% of the participants, respectively (the limits of detection of 0.6-1.2 microg/l). Monomethylarsonic acid was detected in 35% of the overall population. For all participants aged > or =6 years, dimethylarsinic acid (geometric mean of 3.71 microg/l) and arsenobetaine (geometric mean of 1.55 microg/l) had the greatest contribution to the total urinary arsenic levels. A relatively greater percentage contribution from arsenobetaine is seen at higher total urinary arsenic levels and from dimethylarsinic acid at lower total urinary arsenic levels. For all participants aged > or =6 years, the 95th percentiles for total urinary arsenic and the sum of inorganic-related arsenic (arsenic acid, arsenous acid, dimethylarsinic acid, and monomethylarsonic acid) were 65.4 and 18.9 microg/l, respectively. For total arsenic and dimethylarsinic acid, covariate-adjusted geometric means demonstrated several slight differences due to age, gender, and race/ethnicity.
conclusionsThe data reflect relative background contributions of inorganic and seafood-related arsenic exposures in the US population. Arsenobetaine and dimethylarsinic acid are the major arsenic species present with arsenobetaine, accounting for a greater proportion of total arsenic as total arsenic levels increase.
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