Evidence map›Paper›PMID 18523068›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2008

Molecular imaging of metastatic potential.

Paul T Winnard, Arvind P Pathak, Surajit Dhara, Steven Y Cho, Venu Raman, Martin G Pomper

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Noninvasive evaluation ofScientific reports · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Aptamers Selected by Cell-SELEX for Molecular Imaging.Journal of molecular evolution · 2015
    Review
  13. Article
  14. Article
  15. Review
  16. Translation in solid cancer: are size-based response criteria an anachronism?Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2015
    Article
  17. Current progress of aptamer-based molecular imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2014
    Review
  18. Article
  19. Molecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agents.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul T WinnardRussell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore 21231, Maryland, USA.
Arvind P Pathak
Surajit Dhara
Steven Y Cho
Venu Raman
Martin G Pomper

Funding

Theranostic Imaging of Metastatic Prostate CancerP50CA103175 · NCI · JOHNS HOPKINS UNIVERSITY · PI BARKER, PETER B · 2003 to 2015
$17.9M
Interdisciplinary Small Animal Imaging for OncologyR24CA092871 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2001 to 2006
$5.1M
Small Animal Imaging Resource (SAIR)U24CA092871 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2007 to 2011
$2.3M
NCI NIH HHS P50 CA103175NCI NIH HHS R24 CA092871NCI NIH HHS U24 CA092871NCI NIH HHS U24 CA92871
6 · The paper itself

Abstract

If molecular imaging is to prove clinically useful it will have to surpass current, primarily anatomic techniques in terms of sensitivity and the ability to detect minimal changes in tissue. One of the most important tests for molecular imaging is to determine whether it can image the metastatic potential of tumors. Like all predictive endeavors, the imaging of such "potential" is a daunting task, but one that only molecular imaging--rather than standard, anatomic techniques--is likely to solve. Although difficult, imaging of metastatic potential is also arguably the most important task for molecular imaging of cancer because it is generally the dissemination of malignant tissue, not its prolonged residence in an inopportune site, which kills the patient. Below are examples of uses of molecular imaging of metastases as well as of metastatic potential, the former being a far more developed area of clinical inquiry.

Indexed as

AnimalsCell HypoxiaCell MovementHumansLuminescent MeasurementsMagnetic Resonance ImagingMiceNeoplasm InvasivenessNeoplasm MetastasisNeoplasmsPhantoms, ImagingRadiopharmaceuticalsRadiopharmaceuticals

Identifiers

PMID18523068
PMCPMC5516907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.