ArticleCell stem cell2008
Rehabilitation of a contract killer: caspase-3 directs stem cell differentiation.
Article in Cell stem cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Subchondral bone repair potential of an osteochondral scaffold augmented with BMP-2 or strontium-enriched amorphous calcium phosphate: a co-cultureFrontiers in medicine · 2026Article
- In Vitro Inhibition of Colon Cancer Stem Cells by Natural Polysaccharides Obtained from Wheat Cell Culture.Polymers · 2025Article
- miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients.Investigative ophthalmology & visual science · 2025Article
- Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells.Development (Cambridge, England) · 2024Article
- DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?European journal of histochemistry : EJH · 2021Review
- Serum CYFRA 21.1 Level Predicts Disease Course in Thyroid Cancer with Distant Metastasis.Cancers · 2021Article
- Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart.Cell research · 2017Article
- Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner.Blood · 2017Article
- Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis.Scientific reports · 2016Article
- Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Sublethal caspase activation promotes generation of cardiomyocytes from embryonic stem cells.PloS one · 2015Article
- Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival.World journal of gastroenterology · 2014Article
- Dual small-molecule targeting of procaspase-3 dramatically enhances zymogen activation and anticancer activity.Journal of the American Chemical Society · 2014Article
- Article
- Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- The non-death role of metacaspase proteases.Frontiers in oncology · 2012Article
- Regulation of caspase pathways by protein kinase CK2: identification of proteins with overlapping CK2 and caspase consensus motifs.Molecular and cellular biochemistry · 2011Article
- Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.Molecular and cellular biology · 2011Article
- The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation.Circulation research · 2010Article
- Parole terms for a killer: directing caspase3/CAD induced DNA strand breaks to coordinate changes in gene expression.Cell cycle (Georgetown, Tex.) · 2010Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Activation of caspase-3 is generally acknowledged as a penultimate step in apoptotic cell death pathways. Two studies in this issue of Cell Stem Cell (Fujita et al., 2008; Janzen et al., 2008) provide compelling data to demonstrate that caspase-3 is also a conserved inductive cue for stem cell differentiation.
Indexed as
Identifiers
18522841What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.