ArticleBMC cancer2008
Case-control study of tobacco smoke exposure and breast cancer risk in Delaware.
Article in BMC cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- The relationship between tobacco and breast cancer incidence: A systematic review and meta-analysis of observational studies.Frontiers in oncology · 2022Pooled it
- Environmental tobacco smoke exposure and risk of breast cancer in nonsmoking women. An updated review and meta-analysis.Inhalation toxicology · 2016Pooled it
- Smoking before the first pregnancy and the risk of breast cancer: a meta-analysis.American journal of epidemiology · 2011Pooled it
- Health effects associated with exposure to secondhand smoke: a Burden of Proof study.Nature medicine · 2024Article
- Passive Smoking and Breast Cancer Risk among Non-Smoking Women: A Case-Control Study in China.PloS one · 2015Article
- Risk factors for breast cancer in Iranian women: a hospital-based case-control study in tabriz, iran.Journal of breast cancer · 2014Article
- Passive smoking and risk of breast cancer in the California teachers study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundTobacco smoke exposure may be associated with increased breast cancer risk, although the evidence supporting the association is inconclusive. We conducted a case-control study in Delaware, incorporating detailed exposure assessment for active and secondhand smoke at home and in the workplace.
methodsPrimary invasive breast cancer cases diagnosed among female Delaware residents, ages 40-79, in 2000-2002 were identified through the Delaware cancer registry (n = 287). Delaware drivers license and Health Care Finance Administration records were used to select age frequency-matched controls for women <65 and > or = 65, respectively. Detailed information on tobacco smoke exposure was obtained through telephone interviews.
resultsA statistically significant increased risk of breast cancer was observed for ever having smoked cigarettes (odds ratio = 1.43, 95% confidence interval = 1.03-1.99). However, there was no evidence of a dose-response relationship between breast cancer risk and total years smoked, cigarettes per day, or pack-years. Neither residential nor workplace secondhand smoke exposure was associated with breast cancer. Recalculations of active smoking risks using a purely unexposed reference group of women who were not exposed to active or secondhand smoking did not indicate increased risks of breast cancer.
conclusionThese findings do not support an association between smoking and breast cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.