ArticleSleep2008
Quantification of electromyographic activity during REM sleep in multiple muscles in REM sleep behavior disorder.
Article in Sleep, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it.
- REM sleep behavior disorder and REM sleep without atonia as an early manifestation of degenerative neurological disease.Current neurology and neuroscience reports · 2012Pooled it
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- Validation of RBDtector: An Open-Source Automated Software for Scoring REM Sleep Without Atonia.Journal of sleep research · 2025Article
- From mechanisms to future therapy: a synopsis of isolated REM sleep behavior disorder as early synuclein-related disease.Molecular neurodegeneration · 2025Review
- Loss of rapid eye movement atonia in rapid eye movement sleep behaviour disorder and narcolepsy.Journal of sleep research · 2025Article
- Audiovisual analysis of the diagnostic video polysomnography in patients with isolated REM sleep behavior disorder.Journal of neurology · 2025Article
- Validation of the RBD Symptom Severity Scale in the North American Prodromal Synucleinopathy Consortium.Neurology · 2024Article
- Periodic Leg Movements during Sleep Associated with REM Sleep Behavior Disorder: A Machine Learning Study.Diagnostics (Basel, Switzerland) · 2024Article
- Contemporary diagnostic visual and automated polysomnographic REM sleep without atonia thresholds in isolated REM sleep behavior disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Sleep disturbances associated with DPPX autoantibodies: a case series.Journal of neurology · 2023Article
- Article
- Quantitative Network Comparisons of REM Sleep Without Atonia Across the α-Synucleinopathy Spectrum: A Systematic Review.Nature and science of sleep · 2023Article
- Analysis of sleep, daytime sleepiness, and autonomic function in multiple system atrophy and Parkinson disease: a prospective study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- Exploring the Sensitivity of Prodromal Dementia with Lewy Bodies Research Criteria.Brain sciences · 2022Article
- Restricted truncal sagittal movements of rapid eye movement behaviour disorder.NPJ Parkinson's disease · 2022Article
- Article
- Incidence and Progression of Rapid Eye Movement Behavior Disorder in Early Parkinson's Disease.Movement disorders clinical practice · 2021Article
- Association of heart rate variability with REM sleep without atonia in idiopathic REM sleep behavior disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe aim of our study was to determine which muscle or combination of muscles (either axial or limb muscles, lower or upper limb muscles, or proximal or distal limb muscles) provides the highest rates of rapid eye movement (REM) sleep phasic electromyographic (EMG) activity seen in patients with REM sleep behavior disorder (RBD).
settingTwo university hospital sleep disorders centers.
participantsSeventeen patients with idiopathic RBD (n = 8) and RBD secondary to Parkinson disease (n = 9).
interventionsNot applicable. MEASUREMENTS AND
resultsPatients underwent polysomnography, including EMG recording of 13 different muscles. Phasic EMG activity in REM sleep was quantified for each muscle separately. A mean of 1459.6 +/- 613.8 three-second REM sleep mini-epochs were scored per patient. Mean percentages of phasic EMG activity were mentalis (42 +/- 19), flexor digitorum superficialis (29 +/- 13), extensor digitorum brevis (23 +/- 12), abductor pollicis brevis (22 +/- 11), sternocleidomastoid (22 +/- 12), deltoid (19 +/- 11), biceps brachii (19 +/- 11), gastrocnemius (18 +/- 9), tibialis anterior (right, 17 +/- 12; left, 16 +/- 10), rectus femoris (left, 11 +/- 6; right, 9 +/- 6), and thoraco-lumbar paraspinal muscles (6 +/- 5). The mentalis muscle provided significantly higher rates of excessive phasic EMG activity than all other muscles but only detected 55% of all the mini-epochs with phasic EMG activity. Simultaneous recording of the mentalis, flexor digitorum superficialis, and extensor digitorum brevis muscles detected 82% of all mini-epochs containing phasic EMG activity. This combination provided higher rates of EMG activity than any other 3-muscle combination. Excessive phasic EMG activity was more frequent in distal than in proximal muscles, both in upper and lower limbs.
conclusionSimultaneous recording of the mentalis, flexor digitorum superficialis, and extensor digitorum brevis muscles provided the highest rates of REM sleep phasic EMG activity in subjects with RBD.
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