ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2008
Evaluation of liver enzymes following elective laparoscopic cholecystectomy: are they really elevated?
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Pooled it
- Postoperative Cholestasis After Uncomplicated Laparoscopic Cholecystectomy: A Case Report.Case reports in surgery · 2026Article
- A preliminary study using luminol-enhanced intraoperative bile duct imaging technique in rabbits.Scientific reports · 2025Article
- Evaluating liver function test alterations in laparoscopic right adrenalectomy with different retractors.Northern clinics of Istanbul · 2025Article
- Utility of routine blood tests after elective laparoscopic cholecystectomy for symptomatic gallstones.World journal of gastrointestinal surgery · 2017Article
- Laparoscopic Splenectomy for the Elderly Liver Cirrhotic Patients With Hypersplenism: A Retrospective Comparable Study.Medicine · 2016Observational
- Consecutive laparoscopic gallbladder and spleen resections in cirrhotic patients.World journal of gastroenterology · 2014Article
- Portal vein thrombosis after laparoscopic splenectomy during childhood.Journal of thrombosis and thrombolysis · 2014Article
- Long-term postoperative outcomes of hypersplenism: laparoscopic versus open splenectomy secondary to liver cirrhosis.Surgical endoscopy · 2012Article
- Elevation of liver function tests after laparoscopic gastrectomy using a Nathanson liver retractor.World journal of surgery · 2011Article
- Comparison of liver function after laparoscopically assisted and open distal gastrectomies for patients with liver disease.Surgical endoscopy · 2011Article
- Liver function alterations after laparoscopy-assisted gastrectomy for gastric cancer and its clinical significance.World journal of gastroenterology · 2011Article
- Alterations in portal vein blood pH, hepatic functions, and hepatic histology in a porcine carbon dioxide pneumoperitoneum model.Surgical endoscopy · 2010Article
- Routine testing of liver function before and after elective laparoscopic cholecystectomy: is it necessary?JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies made on a small number of patients have demonstrated significant modifications in liver function tests (LFT) following laparoscopic cholecystectomy.
aimTo assess retrospectively, post-operative LFT in a large group of patients undergoing elective uneventful laparoscopic cholecystectomy.
methodsBetween 1999 and 2007, 1,997 patients were scheduled for laparoscopic cholecystectomy. In 1,034 patients (the study group), the surgery was elective and normal LFT were measured a day prior to surgery. Exclusion criteria included acute cholecystitis, acute pancreatitis, pre-operative endoscopic retrograde cholangio-pancreatography, medication that may affect liver metabolism, and intra-operative complications. Liver function tests were evaluated pre-operatively and 20-24 h post-operatively.
resultsThe mean post-operative value of liver function tests and amylase were well within normal limits, although mild increase was inspected in part of it. We observed post-operative mild hepatic enzyme increase only in 41 patients (3.9%), in nine of these, choledocholithiasis was found.
conclusionsIn contrary to previously published data, we have validated, in light of our broad sampling, that the induction of CO(2) pneumoperitoneum does not cause deranged liver function tests.
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