Evidence map›Paper›PMID 18516202›Full record

ArticleThe Clinical biochemist. Reviews2004

A practical approach to using mice in atherosclerosis research.

Stewart C Whitman

Open access · greenAbstract read
In one paragraph

Article in The Clinical biochemist. Reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 128 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Journal of clinical biochemistry and nutrition · 2024
    Article
  5. The effect of HLA-DRB1*04:01 on a mouse model of atherosclerosis.Journal of translational autoimmunity · 2023
    Article
  6. Article
  7. Guidelines on models of diabetic heart disease.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  8. Article
  9. The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification.Journal of cardiovascular development and disease · 2022
    Article
  10. Article
  11. Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stewart C WhitmanThe University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada. swhitman@ottawaheart.ca
University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses the application-side of using mice as an animal model of atherosclerosis, and is directed towards the researcher new to using mice to perform atherosclerosis studies. Although this review will comment on many of the current mouse models that are available, noting their strengths and weaknesses, the majority of this review is relevant to planning experiments involving either apolipoprotein (apo) E deficient or low-density lipoprotein (LDL) receptor deficient mice. Subject matter covered includes a description of the types of lesions expected to form in apoE deficient and LDL receptor deficient mice, the age of the mouse when these various types of lesion are expected to form, and finally, a description of the most popular methods used to perform both biochemical and morphometric analysis of atherosclerotic lesions.

Identifiers

PMID18516202
PMCPMC1853358
OpenAlexW273330572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.