Evidence map›Paper›PMID 18515778›Full record

ArticleJournal of the Royal Society of Medicine2008

Media influence on Herceptin subsidization in Australia: application of the rule of rescue?

Ross Mackenzie, Simon Chapman, Glenn Salkeld, Simon Holding

Abstract read
In one paragraph

Article in Journal of the Royal Society of Medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  3. Review
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  5. Article
  6. Policy Challenges for Organ Allocation in an Era of "Precision Medicine".Canadian journal of kidney health and disease · 2020
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  7. Article
  8. Article
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  10. Review
  11. Article
  12. Article
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  15. Article
  16. Consumer beware: a systematic assessment of potential bias in the lay electronic media to examine the portrayal of "PARP" inhibitors for cancer treatment.Journal of cancer education : the official journal of the American Association for Cancer Education · 2011
    Article
  17. Trick or treat? Australian newspaper portrayal of complementary and alternative medicine for the treatment of cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011
    Article
  18. "No respecter of youth": over-representation of young women in Australian television coverage of breast cancer.Journal of cancer education : the official journal of the American Association for Cancer Education · 2010
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ross MackenzieSchool of Public Health, University of Sydney 2006, Australia.
Simon Chapman
Glenn Salkeld
Simon Holding

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn August 2006, the Australian government announced that Herceptin (Trastuzumab) would be added to the national Pharmaceutical Benefits Scheme (PBS) of government-subsidized drugs, for treatment with adjuvant chemotherapy of HER2 breast cancer. Following initial reticence, the health minister responded to a campaign by patients and patient advocacy groups by announcing PBS subsidization which lowered the cost of a weekly dose from A$1000 to A$30. The cost to the government would be A$470 million over three years for treatment of an estimated 2100 women annually.

designWe analysed the news frames used in all direct and attributed statements (n=239) in television news coverage of the discourse preceding the Herceptin decision by the Australian government.

settingFive Sydney free-to-air channels between October 2005 and August 2006.

main outcome measuresNews frames or themes.

resultsOf five news frames identified, one ('desperate, sick women in double jeopardy because of callous government/incompetent bureaucracy') accounted for 54% of all reported statements. Government financial parsimony was framed as responsible for the women's plight, with drug industry pricing never mentioned. Claimed benefits of Herceptin often conflated cancer non-recurrence and survival and favoured quantification rhetoric which emphasized percentage increases in improvement rather than the more modest increases in absolute survival.

conclusionsNews frames invoking key tenets of the 'rule of rescue' dominated television discourse on Herceptin. Clinicians, patients, their families and patient advocacy groups invoking the rule of rescue can increase the likelihood of achieving their objective of gaining access to expensive healthcare such as pharmaceuticals. Rational, criteria-based public health policy will find it hard to resist the rule of rescue imperative.

Indexed as

Health PolicyMass MediaAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsAustraliaBreast NeoplasmsChemotherapy, AdjuvantFemaleGovernment ProgramsHumansTrastuzumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsTrastuzumab

Identifiers

PMID18515778
PMCPMC2408635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.