Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2008
Preventing late-life depression in age-related macular degeneration.
Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Prevention of depression in adults with long-term physical conditions.The Cochrane database of systematic reviews · 2021Pooled it
- Low vision rehabilitation for better quality of life in visually impaired adults.The Cochrane database of systematic reviews · 2020Pooled it
- Challenges and Solutions for Depression Prevention Research: Methodology for a Depression Prevention Trial for Older Adults with Knee Arthritis and Emotional Distress.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Trial
- Stepped-care to prevent depression and anxiety in visually impaired older adults--design of a randomised controlled trial.BMC psychiatry · 2013Trial
- [The influence of visual rehabilitation on secondary depressive disorders due to age-related macular degeneration. A randomized controlled pilot study].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2013Trial
- Problem-solving strategies of women undergoing chemotherapy for breast cancer.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2012Trial
- Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability.Archives of general psychiatry · 2011Trial
- Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction.The American journal of psychiatry · 2010Trial
- Visual Impairment and Mental Health: Unmet Needs and Treatment Options.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Why visually impaired older adults often do not receive mental health services: the patient's perspective.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Article
- Association of Ophthalmologic Disorders and Depression in the Elderly: A Review of the Literature.The primary care companion for CNS disorders · 2015Article
- The mediating role of disability and social support in the association between low vision and depressive symptoms in older adults.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- Problem-Solving Therapy in the Elderly.Current treatment options in psychiatry · 2014Article
- Association between depression and functional vision loss in persons 20 years of age or older in the United States, NHANES 2005-2008.JAMA ophthalmology · 2013Article
- The psychological challenge of late-life vision impairment: concepts, findings, and practical implications.Journal of ophthalmology · 2013Article
- Problem-solving versus cognitive restructuring of medically ill seniors with depression (PROMISE-D trial): study protocol and design.BMC psychiatry · 2012Article
- Current methods of visual rehabilitation.Deutsches Arzteblatt international · 2011Review
- Depressive symptoms moderate the influence of the apolipoproteine epsilon4 allele on cognitive decline in a sample of community dwelling older adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2009Article
- Major depression during interferon-alpha treatment: vulnerability and prevention.Dialogues in clinical neuroscience · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine whether problem-solving treatment (PST) can prevent depressive disorders in patients with age-related macular degeneration (AMD).
designTwo hundred six patients with AMD were randomly assigned to PST (n = 105) or usual care (n = 101). PST therapists delivered six PST sessions over 8 weeks in subjects' homes. MEASUREMENTS: Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition Diagnoses of Depressive Disorders, Hamilton Depression Rating Scale scores, and rates of relinquishing valued activities were assessed at 2 months for short-term effects and 6 months for maintenance effects.
resultsThe 2-month incidence rate of depressive disorders in PST-treated subjects was significantly lower than controls (11.6% versus 23.2%, respectively; OR = 0.43; 95% CI [0.20, 0.95]). PST also reduced the odds of relinquishing a valued activity (OR = 0.48; 95% CI [0.25, 0.96]); this effect mediated the relationship between treatment group and depression. By 6 months most earlier observed benefits had diminished. Secondary analyses showed that a minimal level of depressive symptoms were disabling and predicted incident depressive disorders.
conclusionPST prevented depressive disorders and loss of valued activities as a short-term treatment but these benefits were not maintained over time. To sustain PST's effect, an intervention that uses a problem-solving framework to enhance rehabilitative skills may be necessary.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.