ArticleThe Plant cell2008
XAP5 CIRCADIAN TIMEKEEPER coordinates light signals for proper timing of photomorphogenesis and the circadian clock in Arabidopsis.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 66 citations in OpenAlex.
- XAP5 CIRCADIAN TIMEKEEPER coordinates circadian rhythms and anthocyanin biosynthesis independently of splicing.Plant physiology · 2026Article
- Conserved eukaryotic factors XCT and COP1 work together to control circadian clock function and reproductive timing in plants.Npj biological timing and sleep · 2026Article
- Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors.eLife · 2025Article
- Article
- XAP5 CIRCADIAN TIMEKEEPER regulates RNA splicing and the circadian clock by genetically separable pathways.Plant physiology · 2023Article
- Global Analysis of Dark- and Heat-Regulated Alternative Splicing in Arabidopsis.International journal of molecular sciences · 2023Article
- Phosphorylation of RNA Polymerase II by CDKC;2 Maintains the Arabidopsis Circadian Clock Period.Plant & cell physiology · 2022Article
- The AGCVIII kinase Dw2 modulates cell proliferation, endomembrane trafficking, and MLG/xylan cell wall localization in elongating stem internodes of Sorghum bicolor.The Plant journal : for cell and molecular biology · 2021Article
- XAP5 CIRCADIAN TIMEKEEPER Affects Both DNA Damage Responses and Immune Signaling inFrontiers in plant science · 2021Article
- Alternative splicing profiling provides insights into the molecular mechanisms of peanut peg development.BMC plant biology · 2020Article
- Development of EST-SSR Markers Linked to Flowering Candidate Genes inPlants (Basel, Switzerland) · 2020Article
- A role forF1000Research · 2020Article
- BIG Regulates Dynamic Adjustment of Circadian Period inPlant physiology · 2018Article
- New class of transcription factors controls flagellar assembly by recruiting RNA polymerase II inProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Sucrose and Ethylene Signaling Interact to Modulate the Circadian Clock.Plant physiology · 2017Article
- The REVEILLE Clock Genes Inhibit Growth of Juvenile and Adult Plants by Control of Cell Size.Plant physiology · 2017Article
- Parallel analysis ofOpen biology · 2017Article
- Article
- Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.EMBO reports · 2014Article
- Wheels within wheels: the plant circadian system.Trends in plant science · 2014Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Numerous, varied, and widespread taxa have an internal circadian clock that allows anticipation of rhythmic changes in the environment. We have identified XAP5 CIRCADIAN TIMEKEEPER (XCT), an Arabidopsis thaliana gene important for light regulation of the circadian clock and photomorphogenesis. XCT is essential for proper clock function: xct mutants display a shortened circadian period in all conditions tested. Interestingly, XCT plays opposite roles in plant responses to light depending both on trait and wavelength. The clock in xct plants is hypersensitive to red but shows normal responses to blue light. By contrast, inhibition of hypocotyl elongation in xct is hyposensitive to red light but hypersensitive to blue light. Finally, XCT is important for ribulose-1,5-bisphosphate carboxylase/oxygenase production and plant greening in response to light. This novel combination of phenotypes suggests XCT may play a global role in coordinating growth in response to the light environment. XCT contains a XAP5 domain and is well conserved across diverse taxa, suggesting it has a common function in higher eukaryotes. Downregulation of the XCT ortholog in Caenorhabditis elegans is lethal, suggesting that studies in Arabidopsis may be instrumental to understanding the biochemical activity of XCT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.