Evidence map›Paper›PMID 18515352›Full record

ArticleNucleic acids research2008

Uprobe 2008: an online resource for universal overgo hybridization-based probe retrieval and design.

Robert T Sullivan, Caroline B Morehouse, NISC Comparative Sequencing Program, James W Thomas

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A W-linked palindrome and gene conversion in New World sparrows and blackbirds.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Robert T SullivanDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Caroline B Morehouse
NISC Comparative Sequencing Program
James W Thomas
National Institutes of Health · USEmory University · US

Funding

Uprobe: A Genome-Wide Resource for Isolating Nonhuman Primate Genomic ClonesR24RR022239 · NCRR · EMORY UNIVERSITY · PI THOMAS, JAMES W · 2006 to 2007
$452k
Intramural NIH HHSNCRR NIH HHS R24 RR022239NCRR NIH HHS R24RR022239
6 · The paper itself

Abstract

Cross-species sequence comparisons are a prominent method for analyzing genomic DNA and an ever increasing number of species are being selected for whole-genome sequencing. Targeted comparative genomic sequencing is a complementary approach to whole-genome shotgun sequencing and can produce high-quality sequence assemblies of orthologous chromosomal regions of interest from multiple species. Genomic libraries necessary to support targeted mapping and sequencing projects are available for more than 90 vertebrates. An essential step for utilizing these and other genomic libraries for targeted mapping and sequencing is the development of the hybridization-based probes, which are necessary to screen a genomic library of interest. The Uprobe website (http://uprobe.genetics.emory.edu) provides a public online resource for identifying or designing 'universal' overgo-hybridization probes from conserved sequences that can be used to efficiently screen one or more genomic libraries from a designated group of species. Currently, Uprobe provides the ability to search or design probes for use in broad groups of species, including mammals and reptiles, as well as more specific clades, including marsupials, carnivores, rodents and nonhuman primates. In addition, Uprobe has the capability to design custom probes from multiple-species sequence alignments provided by the user, thus providing a general tool for targeted comparative physical mapping.

Indexed as

Genomic LibrarySoftwareAnimalsCarnivoraCercopithecidaeDNA ProbesGenomicsHominidaeHumansInternetMarsupialiaPhysical Chromosome MappingRodentiaSequence AlignmentDNA Probes

Identifiers

PMID18515352
PMCPMC2447791
OpenAlexW2146996764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.