Lactate: a major and crucial player in normal function of both muscle and brain.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed.

1. The significance of glycemic variability in conjunction with lactate metabolism levels in the clinical assessment of neonatal hypoxic-ischemic encephalopathy.Scientific reports · 2025
   Article
2. The Feud over Lactate and Its Role in Brain Energy Metabolism: An Unnecessary Burden on Research and the Scientists Who Practice It.International journal of molecular sciences · 2025
   Review
3. Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT-1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide production.Journal of neurochemistry · 2025
   Article
4. Glioma neuron symbiosis: a hypothesis.Frontiers in neuroscience · 2025
   Article
5. Role of Fatty Acids β-Oxidation in the Metabolic Interactions Between Organs.International journal of molecular sciences · 2024
   Review
6. Glycolytic lactate production supports status epilepticus in experimental animals.Annals of clinical and translational neurology · 2023
   Article
7. Tracing the lactate shuttle to the mitochondrial reticulum.Experimental & molecular medicine · 2022
   Review
8. Lactate in contemporary biology: a phoenix risen.The Journal of physiology · 2022
   Article
9. The blood lactate/pyruvate equilibrium affair.American journal of physiology. Endocrinology and metabolism · 2022
   Article
10. Mitochondrial Transport in Glycolysis and Gluconeogenesis: Achievements and Perspectives.International journal of molecular sciences · 2021
    Review
11. Role of the Heart in Lactate Shuttling.Frontiers in nutrition · 2021
    Review
12. The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU.Journal of sport and health science · 2020
    Review
13. The Precious Few Grams of Glucose During Exercise.International journal of molecular sciences · 2020
    Review
14. Lactate as a fulcrum of metabolism.Redox biology · 2020
    Review
15. Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments.Frontiers in neuroscience · 2016
    Review
16. Endogenous Nutritive Support after Traumatic Brain Injury: Peripheral Lactate Production for Glucose Supply via Gluconeogenesis.Journal of neurotrauma · 2015
    Article
17. An Ultra-High Field Magnetic Resonance Spectroscopy Study of Post Exercise Lactate, Glutamate and Glutamine Change in the Human Brain.Frontiers in physiology · 2015
    Article
18. Cerebral metabolism following traumatic brain injury: new discoveries with implications for treatment.Frontiers in neuroscience · 2014
    Review
19. Direct and indirect lactate oxidation in trained and untrained men.Journal of applied physiology (Bethesda, Md. : 1985) · 2013
    Article
20. Intracellular shuttle: the lactate aerobic metabolism.TheScientificWorldJournal · 2012
    Article

Corrections and comments

• Comment on
  Non-selective beta-adrenergic blockade prevents reduction of the cerebral metabolic ratio during exhaustive exercise in humans.2008

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as