ArticleAnnals of human genetics2008
Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India.
Article in Annals of human genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- A reference panel for linkage disequilibrium and genotype imputation using whole-genome sequencing data from 2,680 participants across India.HGG advances · 2026Article
- The importance of accurate phenotyping in large-scale analyses of common disorders such as hearing loss.European journal of human genetics : EJHG · 2025Article
- Ethnogenetic analysis reveals the Bronze Age genetic affiliation of Yashkuns with West Eurasians.Scientific reports · 2024Article
- Privacy-preserving chi-squared test of independence for small samples.BioData mining · 2021Article
- Weighted likelihood inference of genomic autozygosity patterns in dense genotype data.BMC genomics · 2017Article
- Designing genetic association studies for complex traits in India.The Indian journal of medical research · 2017Article
- Extremely low-coverage whole genome sequencing in South Asians captures population genomics information.BMC genomics · 2017Article
- DISSCO: direct imputation of summary statistics allowing covariates.Bioinformatics (Oxford, England) · 2015Article
- Dopaminergic gene polymorphisms and cognitive function in a north Indian schizophrenia cohort.Journal of psychiatric research · 2013Article
- MaCH-admix: genotype imputation for admixed populations.Genetic epidemiology · 2013Article
- ALFRED: an allele frequency resource for research and teaching.Nucleic acids research · 2012Article
- Assessment of genotype imputation performance using 1000 Genomes in African American studies.PloS one · 2012Article
- Single nucleotide polymorphisms and haplotypes in Native American populations.American journal of physical anthropology · 2011Article
- Haplotype variation and genotype imputation in African populations.Genetic epidemiology · 2011Article
- A new likelihood estimator and its comparison with moment estimators of individual genome-wide diversity.Heredity · 2011Article
- A generic coalescent-based framework for the selection of a reference panel for imputation.Genetic epidemiology · 2010Article
- Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa.PloS one · 2010Article
- Genome-wide association studies in diverse populations.Nature reviews. Genetics · 2010Review
- Article
- Practical considerations for imputation of untyped markers in admixed populations.Genetic epidemiology · 2010Article
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8 authors.
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Abstract
When performing association studies in populations that have not been the focus of large-scale investigations of haplotype variation, it is often helpful to rely on genomic databases in other populations for study design and analysis - such as in the selection of tag SNPs and in the imputation of missing genotypes. One way of improving the use of these databases is to rely on a mixture of database samples that is similar to the population of interest, rather than using the single most similar database sample. We demonstrate the effectiveness of the mixture approach in the application of African, European, and East Asian HapMap samples for tag SNP selection in populations from India, a genetically intermediate region underrepresented in genomic studies of haplotype variation.
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