Evidence map›Paper›PMID 18513143›Full record

ArticleBehavioral neuroscience2008

Eyeblink classical conditioning in the preweanling lamb.

Timothy B Johnson, Mark E Stanton, Charles R Goodlett, Timothy A Cudd

Abstract read
In one paragraph

Article in Behavioral neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Young Domestic PigsFrontiers in behavioral neuroscience · 2021
    Article
  2. Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children.Journal of visualized experiments : JoVE · 2018
    Article
  3. Review
  4. Article
  5. Article
  6. Eyeblink conditioning in the developing rabbit.Developmental psychobiology · 2012
    Article
  7. Fetal alcohol spectrum disorders and abnormal neuronal plasticity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2011
    Review
  8. Focus on: the use of animal models for the study of fetal alcohol spectrum disorders.Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2011
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Timothy B JohnsonDepartment of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4466, USA. timjohnson@tamu.edu
Mark E Stanton
Charles R Goodlett
Timothy A Cudd

Funding

OVINE MODEL SYSTEM FOR ALCOHOL RELATED BIRTH DEFECTSR01AA010940 · NIAAA · TEXAS A&M UNIVERSITY SYSTEM · PI WASHBURN, SHANNON E. · 1997 to 2012
$3.5M
Translational Studies of FASD Using a Sheep Model-U01U01AA017120 · NIAAA · TEXAS A&M AGRILIFE RESEARCH · PI WASHBURN, SHANNON E. · 2007 to 2011
$1.3M
Functional measure of 3rd trimester FASD: neonatal sheepR21AA015339 · NIAAA · TEXAS A&M UNIVERSITY SYSTEM · PI CUDD, TIMOTHY A · 2005 to 2006
$342k
NIAAA NIH HHS R01 AA010940NIAAA NIH HHS R21 AA015339NIAAA NIH HHS U01 AA017120
6 · The paper itself

Abstract

Classical conditioning of eyeblink responses has been one of the most important models for studying the neurobiology of learning, with many comparative, ontogenetic, and clinical applications. The current study reports the development of procedures to conduct eyeblink conditioning in preweanling lambs and demonstrates successful conditioning using these procedures. These methods will permit application of eyeblink conditioning procedures in the analysis of functional correlates of cerebellar damage in a sheep model of fetal alcohol spectrum disorders, which has significant advantages over more common laboratory rodent models. Because sheep have been widely used for studies of pathogenesis and mechanisms of injury with many different prenatal or perinatal physiological insults, eyeblink conditioning can provide a well-studied method to assess postnatal behavioral outcomes, which heretofore have not typically been pursued with ovine models of developmental insults.

Indexed as

BlinkingAcoustic StimulationAnalysis of VarianceAnimalsAnimals, NewbornBehavior, AnimalConditioning, ClassicalDiscrimination LearningEye Protective DevicesFemaleMaleReaction TimeSex FactorsSheep

Identifiers

PMID18513143
PMCPMC2925182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.