Evidence map›Paper›PMID 18512093›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2008

Prehospital cooling with hypothermia caps (PreCoCa): a feasibility study.

Christian Storm, Joerg C Schefold, Thoralf Kerner, Willi Schmidbauer, Jola Gloza, Anne Krueger, Achim Jörres, Dietrich Hasper

Abstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Anti-platelet Therapy Resistance - Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2016
    Article
  4. Therapeutic hypothermia for acute neurological injuries.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2012
    Review
  5. Coronary angiography and intervention during hypothermia can be performed safely without cardiac arrhythmia or vasospasm.Clinical research in cardiology : official journal of the German Cardiac Society · 2011
    Article
  6. Autonomic regulation during mild therapeutic hypothermia in cardiopulmonary resuscitated patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2011
    Article
  7. Effects of mild hypothermia on hemodynamics in cardiac arrest survivors and isolated failing human myocardium.Clinical research in cardiology : official journal of the German Cardiac Society · 2010
    Article
  8. Prehospital therapeutic hypothermia after cardiac arrest--from current concepts to a future standard.Scandinavian journal of trauma, resuscitation and emergency medicine · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christian StormDepartment of Nephrology and Medical, Intensive Care Medicine, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
Joerg C Schefold
Thoralf Kerner
Willi Schmidbauer
Jola Gloza
Anne Krueger
Achim Jörres
Dietrich Hasper

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnimal studies suggest that the induction of therapeutic hypothermia in patients after cardiac arrest should be initiated as soon as possible after ROSC to achieve optimal neuroprotective benefit. A "gold standard" for the method of inducing hypothermia quickly and safely has not yet been established. In order to evaluate the feasibility of a hypothermia cap we conducted a study for the prehospital setting. METHODS AND

resultsThe hypothermia cap was applied to 20 patients after out-of-hospital cardiac arrest with a median of 10 min after ROSC (25/75 IQR 8-15 min). The median time interval between initiation of cooling and hospital admission was 28 min (19-40 min). The median tympanic temperature before application of the hypothermia cap was 35.5 degrees C (34.8-36.3). Until hospital admission we observed a drop of tympanic temperature to a median of 34.4 degrees C (33.6-35.4). This difference was statistically significant (P < 0.001). We could not observe any side effects related to the hypothermia cap. 25 patients who had not received prehospital cooling procedures served as a control group. Temperature at hospital admission was 35.9 degrees C (35.3-36.4). This was statistically significant different compared to patients treated with the hypothermia cap (P < 0.001).

conclusionsIn summary we demonstrated that the prehospital use of hypothermia caps is a safe and effective procedure to start therapeutic hypothermia after cardiac arrest. This approach is rapidly available, inexpensive, non-invasive, easy to learn and applicable in almost any situation.

Indexed as

AdultEmergency Medical ServicesEquipment DesignEquipment Failure AnalysisFeasibility StudiesFemaleHeart ArrestHumansHypothermia, InducedMaleMiddle AgedTreatment Outcome

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.