Evidence map›Paper›PMID 18511714›Full record

ArticleAmerican journal of public health2008

Chronic conditions and mortality among the oldest old.

Sei J Lee, Alan S Go, Karla Lindquist, Daniel Bertenthal, Kenneth E Covinsky

Abstract read
In one paragraph

Article in American journal of public health, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Article
  3. Healthcare contact days among older adults living with dementia.Journal of the American Geriatrics Society · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cognitive and vascular function in older adults with and without CKD.Aging clinical and experimental research · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Neuropsychological Test Norms in Cognitively Intact Oldest-Old.Journal of the International Neuropsychological Society : JINS · 2019
    Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sei J LeeSan Francisco Veterans Affairs Medical Center, Health Services Research and Development Research Enhancement Award Program, San Francisco, CA 94121, USA. sei.lee@ucsf.edu
Alan S Go
Karla Lindquist
Daniel Bertenthal
Kenneth E Covinsky

Funding

Study of the Care and Outcomes of REnal InsufficiencyU01DK060902 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2001 to 2025
$19.5M
HMO Research Network Cardiovascular Research NetworkU19HL091179 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2007 to 2011
$8.7M
RESEARCH TRAINING IN GERIATRIC MEDICINET32AG000212 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 1991 to 2026
$7.7M
Midcareer Mentoring Award for Patient-Oriented Research in AgingK24AG029812 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COVINSKY, KENNETH E. · 2007 to 2017
$1.8M
Diseases/function/self-health in risk indices for eldersR01AG023626 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI COVINSKY, KENNETH E. · 2004 to 2006
$852k
NHLBI NIH HHS HL091179NHLBI NIH HHS U19 HL091179NIA NIH HHS K24 AG029812NIA NIH HHS R01 AG023626NIA NIH HHS T32 AG000212NIA NIH HHS T32 AG000212-15NIDDK NIH HHS DK060902NIDDK NIH HHS U01 DK060902
6 · The paper itself

Abstract

objectivesWe sought to determine whether chronic conditions and functional limitations are equally predictive of mortality among older adults.

methodsParticipants in the 1998 wave of the Health and Retirement Study (N=19430) were divided into groups by decades of age, and their vital status in 2004 was determined. We used multivariate Cox regression to determine the ability of chronic conditions and functional limitations to predict mortality.

resultsAs age increased, the ability of chronic conditions to predict mortality declined rapidly, whereas the ability of functional limitations to predict mortality declined more slowly. In younger participants (aged 50-59 years), chronic conditions were stronger predictors of death than were functional limitations (Harrell C statistic 0.78 vs. 0.73; P=.001). In older participants (aged 90-99 years), functional limitations were stronger predictors of death than were chronic conditions (Harrell C statistic 0.67 vs. 0.61; P=.004).

conclusionsThe importance of chronic conditions as a predictor of death declined rapidly with increasing age. Therefore, risk-adjustment models that only consider comorbidities when comparing mortality rates across providers may be inadequate for adults older than 80 years.

Indexed as

Health BehaviorHealth StatusActivities of Daily LivingAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedModels, StatisticalPredictive Value of TestsProportional Hazards ModelsReproducibility of ResultsRisk AdjustmentSeverity of Illness Index

Identifiers

PMID18511714
PMCPMC2424085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.