Evidence map›Paper›PMID 18511173›Full record

ReviewBiological psychology2008

Neurobiology of cognitive aging: insights from imaging genetics.

Venkata S Mattay, Terry E Goldberg, Fabio Sambataro, Daniel R Weinberger

Open access · greenAbstract readReview
In one paragraph

Review in Biological psychology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 72 citations in OpenAlex.

  1. From adolescence to Alzheimer's: a neurodevelopmental lifespan model of cognitive vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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  8. Neuropsychiatric disease and treatment · 2020
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Venkata S MattayGenes, Cognition and Psychosis Program, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, MD 20892, USA. vsm@mail.nih.gov
Terry E Goldberg
Fabio Sambataro
Daniel R Weinberger
National Institute of Mental Health · USFeinstein Institute for Medical Research · US

Funding

MRI Studies of Brain Function and MetabolismZIAMH002716 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BERMAN, KAREN FAITH · 2009 to 2013
$9.8M
Neuroimaging Core FacilityZICMH002905 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BERMAN, KAREN FAITH · 2009 to 2012
$3.8M
Neuroimaging Core FacilityZ01MH002905 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WEINBERGER, DANIEL · 2007 to 2008
$2.6M
Intramural NIH HHS Z01 MH002905Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIC MH002905
6 · The paper itself

Abstract

Over the last several years, neuroscientists have been increasingly using neuroimaging techniques to unravel the neurobiology underlying cognitive aging, and in more recent years to explore the role of genes on the variability of the aging process. One of the primary goals of this research is to identify proteins involved in cognitive aging with the hope that this would facilitate the development of novel treatments to combat cognitive impairment. Further, it is likely with early identification of susceptible individuals, early intervention through life-style changes and other methods could increase an individual's resilience to the effects of aging.

Indexed as

AgingAnimalsCognitionHumansIndividualityMagnetic Resonance ImagingMolecular BiologyNeuropsychological TestsSynaptic Transmission

Identifiers

PMID18511173
PMCPMC3127547
OpenAlexW1977233962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.