Evidence map›Paper›PMID 18510888›Full record

ArticleCurrent infectious disease reports2008

Update on male circumcision: prevention success and challenges ahead.

Kristine E Johnson, Thomas C Quinn

Abstract read
In one paragraph

Article in Current infectious disease reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Gender and AIDS: time to act.AIDS (London, England) · 2008
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristine E JohnsonDivision of Infectious Diseases, Johns Hopkins University School of Medicine, 1830 East Monument Street, Room #401, Baltimore, MD 21205, USA. kjohns87@jhmi.edu
Thomas C Quinn

Funding

International Center for Excellence in Research (ICER) in Uganda: Impact of ARVsZIAAI001040 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REYNOLDS, STEVEN · 2009 to 2025
$23.5M
International Studies of the Acquired Immune Deficiency Syndrome (AIDS)ZIAAI000361 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REDD, ANDREW · 2009 to 2025
$15.8M
INTERNATIONAL STUDIES ON THE ACQUIRED IMMUNODEFICIENCY SYNDROMEZ01AI000361 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI QUINN, THOMAS · 1985 to 2008
$3.1M
Intramural NIH HHS Z01 AI000361
6 · The paper itself

Abstract

This article reviews the findings of three trials of male circumcision for HIV prevention, with emphasis on the public health impact, cultural and safety concerns, implications for women, and the challenges of roll out. Three randomized trials in Africa demonstrated that adult male circumcision reduces HIV acquisition by 50% to 60%. As circumcision provides only partial protection, higher risk behaviors could nullify circumcision's effect. Additionally, circumcision among HIV-infected men does not directly reduce male-to-female HIV transmission among discordant couples, according to the results of a recent Ugandan study. The roll-out or full-scale implementation requires committed expansion into existing HIV prevention programs. Efforts should include attention to safety, implications for women, and risk compensation. Rapid, careful establishment of circumcision services is essential to optimize HIV prevention in countries with the highest prevalence.

Identifiers

PMID18510888
PMCPMC2711844

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.