ArticleCurrent infectious disease reports2008
The effect of vaccination on Streptococcus pneumoniae resistance.
Article in Current infectious disease reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Antibiotic Susceptibility ofAntibiotics (Basel, Switzerland) · 2021Article
- Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries.BMC infectious diseases · 2018Article
- Nasopharyngeal carriage of Streptococcus pneumoniae in healthy Turkish children after the addition of PCV7 to the national vaccine schedule.European journal of pediatrics · 2014Article
- Risk factors for nasopharyngeal carriage of drug-resistant Streptococcus pneumoniae: data from a nation-wide surveillance study in Greece.BMC infectious diseases · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the introduction of the 7-valent pneumococcal conjugate vaccine (PCV-7) in the routine immunization schedule of US children, the morbidity and mortality associated with Streptococcus pneumoniae infections have changed considerably. Post-licensure data from the United States have confirmed that PCV-7 has significantly decreased the incidence of vaccine-type susceptible and antibiotic-resistant invasive pneumococcal diseases, community-acquired respiratory infections, and nasopharyngeal colonization in vaccinated individuals and their contacts. An unintended consequence of immunization with PCV-7 is the simultaneous increase in the carriage rates of non-vaccine-serotype pneumococci (some of which are highly antibiotic-resistant) among vaccinated children (ie, replacement phenomenon). Neither the implications of increased non-vaccine-type colonization nor the additional role of inappropriate antibiotic use in this process is clearly understood, but the greatest concern is that replacement colonization may result in replacement disease. Future vaccination with PCV-7 in European countries could provide additional information.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.