ArticleCardiovascular ultrasound2008
Economic analysis including long-term risks and costs of alternative diagnostic strategies to evaluate patients with chest pain.
Article in Cardiovascular ultrasound, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- The Dangerous Liaison Between Depression and Cardiovascular Disease: A Narrative Review of Epidemiology, Mechanisms, and Clinical Management.Journal of clinical medicine · 2026Review
- Periprocedural Myocardial Infarction: Do We Need an Updated Definition?Journal of cardiovascular development and disease · 2026Review
- An Innovative Model for Diagnosing Lesions in Coronary Angiography Imagery Using an Improved YOLOv4 Model.Bioengineering (Basel, Switzerland) · 2025Article
- Impact of Newly Diagnosed Cancer on Bleeding Events in Patients with Atrial Fibrillation Treated with Direct Oral Anticoagulants.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024Article
- Cardiovascular Imaging for Coronary Artery Disease in Patients with Diabetes Mellitus.Journal of clinical medicine · 2024Review
- Heart Rate Recovery as a Predictor of Long-Term Adverse Events after Negative Exercise Testing in Patients with Chest Pain and Pre-Test Probability of Coronary Artery Disease from 15% to 65.Diagnostics (Basel, Switzerland) · 2023Article
- Medication and ECG Patterns That May Hinder SPECT Myocardial Perfusion Scans.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Coronary Angiography Upgraded by Imaging Post-Processing: Present and Future Directions.Diagnostics (Basel, Switzerland) · 2023Review
- Real world hospital costs following stress echocardiography in the UK: a costing study from the EVAREST/BSE-NSTEP multi-entre study.Echo research and practice · 2023Article
- Predictors of Long-Term Mortality in Patients with Stable Angina Pectoris and Coronary Slow Flow.Medicina (Kaunas, Lithuania) · 2023Article
- Long-term Cost-Effectiveness of Diagnostic Tests for Assessing Stable Chest Pain: Modeled Analysis of Anatomical and Functional Strategies.Clinical cardiology · 2016Article
- Stress-echocardiography is underused in clinical practice: a nationwide survey in Austria.Wiener klinische Wochenschrift · 2015Article
- Echocardiography to supplement stress electrocardiography in emergency department chest pain patients.The western journal of emergency medicine · 2010Article
- Cardiac magnetic resonance imaging for the diagnosis of coronary artery disease: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- Stress echocardiography with contrast for the diagnosis of coronary artery disease: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- 64-slice computed tomographic angiography for the diagnosis of intermediate risk coronary artery disease: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- Single photon emission computed tomography for the diagnosis of coronary artery disease: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- Stress echocardiography for the diagnosis of coronary artery disease: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- Radiation burden in myocardial imaging: an old concern in the new age of hi-tech, hybrid imaging.European journal of nuclear medicine and molecular imaging · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiagnosis costs for cardiovascular disease waste a large amount of healthcare resources. The aim of the study is to evaluate the clinical and economic outcomes of alternative diagnostic strategies in low risk chest pain patients.
methodsWe evaluated direct and indirect downstream costs of 6 strategies: coronary angiography (CA) after positive troponin I or T (cTn-I or cTnT) (strategy 1); after positive exercise electrocardiography (ex-ECG) (strategy 2); after positive exercise echocardiography (ex-Echo) (strategy 3); after positive pharmacologic stress echocardiography (PhSE) (strategy 4); after positive myocardial exercise stress single-photon emission computed tomography with technetium Tc 99m sestamibi (ex-SPECT-Tc) (strategy 5) and direct CA (strategy 6).
resultsThe predictive accuracy in correctly identifying the patients was 83,1% for cTn-I, 87% for cTn-T, 85,1% for ex-ECG, 93,4% for ex-Echo, 98,5% for PhSE, 89,4% for ex-SPECT-Tc and 18,7% for CA. The cost per patient correctly identified results $2.051 for cTn-I, $2.086 for cTn-T, $1.890 for ex-ECG, $803 for ex-Echo, $533 for PhSE, $1.521 for ex-SPECT-Tc ($1.634 including cost of extra risk of cancer) and $29.673 for CA ($29.999 including cost of extra risk of cancer). The average relative cost-effectiveness of cardiac imaging compared with the PhSE equal to 1 (as a cost comparator), the relative cost of ex-Echo is 1.5x, of a ex-SPECT-Tc is 3.1x, of a ex-ECG is 3.5x, of cTnI is x3.8, of cTnT is x3.9 and of a CA is 56.3x.
conclusionStress echocardiography based strategies are cost-effective versus alternative imaging strategies and the risk and cost of radiation exposure is void.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.