Evidence map›Paper›PMID 18510612›Full record

ArticleThe American journal of gastroenterology2008

Relation of bowel habits to fecal incontinence in women.

Adil E Bharucha, Barbara M Seide, Alan R Zinsmeister, L Joseph Melton

Open access · greenAbstract read
In one paragraph

Article in The American journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Global Prevalence of Fecal Incontinence in Community-Dwelling Adults: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Pooled it
  2. Trial
  3. Effects of clonidine in women with fecal incontinence.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2014
    Trial
  4. Symptoms of Constipation: Relationship Between Questionnaires and Diaries and Impact on Quality of Life.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  5. Review
  6. Article
  7. Faecal incontinence in adults.Nature reviews. Disease primers · 2022
    Review
  8. Article
  9. Constipation and Fecal Incontinence in the Elderly.Current gastroenterology reports · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. A Low FODMAP Diet May Reduce Symptoms in Patients With Fecal Incontinence.Clinical and translational gastroenterology · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. A simple bowel habit score for colorectal patients.International journal of colorectal disease · 2017
    Article
  18. Review
  19. Functional Anorectal Disorders.Gastroenterology · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Adil E BharuchaDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Barbara M Seide
Alan R Zinsmeister
L Joseph Melton
Mayo Clinic · USCancer Research And Biostatistics · USHaute École de la Province de Liège · BE

Funding

ZESTRIL VS. VERAPAMIL IN THE TREATMENT OF HYPERTENSIONM01RR000585 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 1985 to 2006
$30.4M
ROCHESTER EPIDEMIOLOGY PROJECTR01AR030582 · NIAMS · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A · 1986 to 2009
$5.1M
Epidemiology and Mechanisms of Fecal IncontinenceR01HD041129 · NICHD · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI BHARUCHA, ADIL E. · 2001 to 2005
$1.5M
NCRR NIH HHS M01 RR000585NCRR NIH HHS M01 RR00585NIAMS NIH HHS R01 AR030582NIAMS NIH HHS R01 AR30582NICHD NIH HHS R01 HD041129NICHD NIH HHS R01 HD41129
6 · The paper itself

Abstract

backgroundThough most women with fecal incontinence (FI) have anorectal dysfunctions, a majority have intermittent symptoms. Variations in bowel habits and daily routine may partly explain this.

aimTo compare bowel habits and daily routine between controls and FI, and between continent and incontinent stools among women with FI.

methodUsing a mailed questionnaire, we identified 507 women with FI among 5,300 women in Olmsted County, MN. Bowel habits were compared among 127 randomly selected controls and 154 women with self-reported FI, who did ("active" FI, N = 106) or did not ("inactive" FI, N = 48) have an incontinent episode during a 2-wk bowel diary period.

resultsIndependent risk factors for FI were: rectal urgency (odds ratio [OR] for inactive FI vs controls 5.6, 95% confidence interval [CI] 2.3-13.3; and OR for active FI vs inactive FI 2.0, 95% CI 0.9-4.3) and a sense of incomplete evacuation (OR for inactive FI vs controls 3.5, 95% CI 1.4-8.8; and OR for active FI vs inactive FI 2.2, 95% CI 1.1-4.9). Similar results were found for stool frequency and form. Among incontinent women, incontinent stools (versus continent stools) were less formed, more likely to occur at work, and to be preceded by rectal urgency.

conclusionsBowel patterns, rectal urgency, and daily routine influence the occurrence of FI. Stool characteristics explained 46% of the likelihood for incontinence episodes, emphasizing that anorectal sensorimotor dysfunctions must also contribute to FI in women.

Indexed as

HabitsCase-Control StudiesCircadian RhythmDefecationFecal IncontinenceFeeding BehaviorFemaleHumansMiddle AgedMotor ActivityRisk FactorsSex Factors

Identifiers

PMID18510612
PMCPMC2536490
OpenAlexW2063142306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.