ArticlePlant cell reports2008
Mammalian pro-apoptotic bax gene enhances tobacco resistance to pathogens.
Article in Plant cell reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Specific and efficient translation inhibition-transcription activation resistance module against viruses in plants.Science advances · 2026Article
- TAL effector-dependent Bax gene expression in transgenic rice confers disease resistance to Xanthomonas oryzae pv. oryzae.Transgenic research · 2022Article
- TaClpS1, negatively regulates wheat resistance against Puccinia striiformis f. sp. tritici.BMC plant biology · 2020Article
- A Phytophthora sojae effector suppresses endoplasmic reticulum stress-mediated immunity by stabilizing plant Binding immunoglobulin Proteins.Nature communications · 2016Article
- Phytophthora capsici homologue of the cell cycle regulator SDA1 is required for sporangial morphology, mycelial growth and plant infection.Molecular plant pathology · 2016Article
- A Virulence Essential CRN Effector of Phytophthora capsici Suppresses Host Defense and Induces Cell Death in Plant Nucleus.PloS one · 2015Article
- Phytophthora sojae avirulence effector Avr3b is a secreted NADH and ADP-ribose pyrophosphorylase that modulates plant immunity.PLoS pathogens · 2011Article
Corrections and comments
- Erratum issuedSuomeng, Dong [corrected to Dong, Suomeng]; Zhengguang, Zhang [corrected to Zhang, Zhengguang]; Xiaobo, Zheng [corrected to Zheng, Xiaobo]; Yuanchao, Wang [corrected to Wang, Yuanchao]
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence suggests that plants and animals may share certain biochemical commonalities in apoptosis, or programmed cell death (PCD) pathways, though plants lack key animal apoptosis related genes. In plants, PCD has many important functions including a role in immunity and resistance to pathogen infection. In this study, a rice phenylalanine ammonia-lyase promoter is used to regulate the expression of the mouse pro-apoptotic bax gene in transgenic tobacco plants. Ectopic expression of the bax negatively affects the growth of transgenic plants. Nonetheless, results show that the bax transgene is induced upon infection by plant pathogens and accumulation of Bax is observed by Western blot analysis. By estimating and measuring the extent of cell death, release of active oxygen species, and accumulation defense-associated gene transcripts, it is shown that bax transgenic plants mount a more robust cell death response compared to control plants. The bax transgenic tobacco plants are also more resistant to infection by Phytophthora parasitica and Ralstonia solanacearum, but have no obvious resistance to tobacco mosaic virus. These results substantiate past studies and illustrate the powerful effects mammalian bax genes may have on plant development and disease resistance.
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