ArticleIntensive care medicine2008
Non-invasive assessment of intracranial pressure using ocular sonography in neurocritical care patients.
Article in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 182 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Ocular Point of Care Ultrasound in Diagnosing Retinal Detachment in the Emergency Department: A Prospective Study.
Evaluation of Cerebral Microcirculation Using Non-invasive Contrast-enhanced Ultrasound and Microbubbles Sonovue Administration After Clinical Cardiorespiratory Arrest
Comparison of Optic Nerve Sheath Diameter and Cerebral Regional Oxygen Saturation Measurements Between General and Spinal Anesthesia Applications in C-Section
Comparison of the Effects of Low-Flow and High-Flow Desflurane Anesthesia on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Surgeries
Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Assessed by Optic Nerve Sheath Diameter and Carotid Doppler Ultrasonography: a Prospective Observational Study
Who cites it
182 citing papers in PubMed, 7 syntheses or guidelines pooled it, 414 citations in OpenAlex.
- Operator and Modality-Dependent Limitations of Optic Nerve Sheath Diameter Sonography for Raised ICP in TBI: A Meta-Regression of Diagnostic Accuracy.Neurocritical care · 2026Pooled it
- Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- Brain ultrasonography: methodology, basic and advanced principles and clinical applications. A narrative review.Intensive care medicine · 2019Pooled it
- Optic nerve sheath diameter measured sonographically as non-invasive estimator of intracranial pressure: a systematic review and meta-analysis.Intensive care medicine · 2018Pooled it
- Ultrasonographic optic nerve sheath diameter for predicting elevated intracranial pressure during laparoscopic surgery: a systematic review and meta-analysis.Surgical endoscopy · 2018Pooled it
- Ultrasonography of optic nerve sheath diameter for detection of raised intracranial pressure: a systematic review and meta-analysis.Intensive care medicine · 2011Pooled it
- Intraindividual Optic Nerve Sheath Variation and Intracranial Pressure Changes: A Systematic Review and Meta-Analysis.Journal of neuroimaging : official journal of the American Society of NeuroimagingPooled it
- Association Between Local Anesthetic Volume-Dose Combinations and Optic Nerve Sheath Diameter as an Indirect Marker of Intracranial Pressure During Ultrasound-Guided Supraclavicular Brachial Plexus Block: A Randomized Trial.Medicina (Kaunas, Lithuania) · 2026Trial
- Ultrasound Measurement of Dynamic Changes in Optic Nerve Sheath Diameter During Liposuction Surgery: A Prospective Clinical Trial.Aesthetic plastic surgery · 2026Trial
- Impact of Low-Dose Ketamine Infusion on Intracranial Pressure and Hemodynamics in Septic Shock Patients.Neurocritical care · 2026Trial
- Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease.Acta neurologica Belgica · 2024Trial
- Comparison of the effect of sevoflurane and propofol on the optic nerve sheath diameter in patients undergoing middle ear surgery.Journal of anesthesia · 2023Trial
- Epidural bolus versus continuous epidural infusion analgesia on optic nerve sheath diameter in paediatric patients: A prospective, double-blind, randomised trial.Scientific reports · 2020Trial
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- Does Tourniquet Time or Pressure Contribute to Intracranial Pressure Increase following Tourniquet Application?Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019Trial
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- Propofol attenuates the increase of sonographic optic nerve sheath diameter during robot-assisted laparoscopic prostatectomy: a randomized clinical trial.BMC anesthesiology · 2018Trial
- Correlation of optic nerve sheath diameter with directly measured intracranial pressure in Korean adults using bedside ultrasonography.PloS one · 2017Trial
- Impact of controlled intraabdominal pressure on the optic nerve sheath diameter during laparoscopic procedures.Surgical endoscopy · 2016Trial
122 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the relationship between optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in neurocritical care patients.
designProspective, observational study.
settingSurgical critical care unit, level 1 trauma center. PATIENTS: A total number of 37 adult patients requiring sedation and ICP monitoring after severe traumatic brain injury, subarachnoid hemorrhage, intracranial hematoma, or stroke. MEASUREMENTS AND MAIN
resultsOptic nerve sheath diameter was measured with a 7.5 MHz linear ultrasound probe. ICP was measured invasively via a parenchymal device. Simultaneous measurements were performed at least once a day during the first 2 days after ICP insertion and in cases of acute changes. There was a significant relationship between ONSD and ICP (78 simultaneous measures, r = 0.71, P < 0.0001). Changes in ICP were strongly correlated with changes in ONSD (39 measures, r = 0.73, P < 0.0001). Enlarged ONSD was a suitable predictor of elevated ICP (>20 mmHg) (area under ROC curve = 0.91). When ONSD was less than 5.86 mm, the negative likehood ratio for raised ICP was 0.06.
conclusionIn sedated neurocritical care patients, non-invasive sonographic measurements of ONSD are correlated with invasive ICP, and the probability to have raised ICP if ONSD is less than 5.86 mm is very low. This method could be used as a screening test when raised ICP is suspected.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.