ReviewFrontiers in bioscience : a journal and virtual library2008
G-protein coupled chemoattractant receptors and cancer.
Review in Frontiers in bioscience : a journal and virtual library, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Tissue-resident memory CD8+T cells might enhance HBV DNA clearance in CHB patients with MASLD complication and normal ALT via the CCL-CCR pathways.Frontiers in cellular and infection microbiology · 2025Article
- Annexin A1 and its receptor gene polymorphisms in systemic lupus erythematosus in the Tunisian population.Clinical rheumatology · 2022Article
- Chemokines in homeostasis and diseases.Cellular & molecular immunology · 2018Review
- Regulation of inflammation by members of the formyl-peptide receptor family.Journal of autoimmunity · 2017Review
- Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinoma.Oncotarget · 2016Article
- Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer.Oncotarget · 2016Article
- Formylpeptide receptor 1 mediates the tumorigenicity of human hepatocellular carcinoma cells.Oncoimmunology · 2016Article
- Allosteric Modulation of Chemoattractant Receptors.Frontiers in immunology · 2016Review
- Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells.BMC cancer · 2014Article
- The role of chemoattractant receptors in shaping the tumor microenvironment.BioMed research international · 2014Review
- Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival.World journal of surgical oncology · 2012Article
- Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptors.PloS one · 2012Article
- CXCL12 mediates trophic interactions between endothelial and tumor cells in glioblastoma.PloS one · 2012Article
- Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells.International immunopharmacology · 2011Review
- Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through the formyl peptide receptor 1.The American journal of pathology · 2011Article
- The cross-talk between the urokinase receptor and fMLP receptors regulates the activity of the CXCR4 chemokine receptor.Cellular and molecular life sciences : CMLS · 2011Article
- [Gd@C(82)(OH)(22)](n) nanoparticles inhibit the migration and adhesion of glioblastoma cells.Oncology letters · 2010Article
- Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with beta-catenin.International journal of colorectal disease · 2010Article
- Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis.Cancer prevention research (Philadelphia, Pa.) · 2010Article
- Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.Carcinogenesis · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Chemoattractant receptors are a group of seven transmembrane, G protein coupled receptors (GPCRs). They were initially identified mainly on leukocytes to mediate cell migration in response to pathogen or host-derived chemotactic factors. During the past decade, chemoattractant GPCRs have been discovered not only to mediate leukocyte chemotaxis thus promoting innate and adaptive host immune responses, but also to play essential roles in development, homeostasis, HIV infection, angiogenesis and wound healing. A growing body of evidence further indicates that chemoattractant GPCRs contribute to tumor growth, invasion, angiogenesis/angiostasis and metastasis. The diverse properties of GPCRs in the progression of malignant tumors have attracted intense interest in their potential as novel anti-tumor pharmacological targets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.