Evidence map›Paper›PMID 18508271›Full record

ReviewTrends in microbiology2008

The role of complex carbohydrate catabolism in the pathogenesis of invasive streptococci.

Samuel A Shelburne, Michael T Davenport, David B Keith, James M Musser

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 116 citations in OpenAlex.

  1. Article
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  3. Review
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  7. Role of Metabolic Adaptation ofPathogens (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Inhibition ofMicrobiology (Reading, England) · 2022
    Article
  12. Article
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  15. Article
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  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Samuel A ShelburneSection of Infectious Diseases, Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Michael T Davenport
David B Keith
James M Musser
Baylor College of Medicine · USHouston Methodist · US

Funding

Analysis Of Group A Streptococcus-Saliva InteractionK08AI064564 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHELBURNE, SAMUEL A · 2006 to 2009
$492k
NIAID NIH HHS K08 AI-064564NIAID NIH HHS K08 AI064564
6 · The paper itself

Abstract

Historically, the study of bacterial catabolism of complex carbohydrates has contributed to understanding basic bacterial physiology. Recently, however, genome-wide screens of streptococcal pathogenesis have identified genes encoding proteins involved in complex carbohydrate catabolism as participating in pathogen infectivity. Subsequent studies have focused on specific mechanisms by which carbohydrate utilization proteins might contribute to the ability of streptococci to colonize and infect the host. Moreover, transcriptome and biochemical analyses have uncovered novel regulatory pathways by which streptococci link environmental carbohydrate availability to virulence factor production. Herein we review new insights into the role of complex carbohydrates in streptococcal host-pathogen interaction.

Indexed as

Carbohydrate MetabolismAnimalsBacteremiaBacterial ProteinsHost-Pathogen InteractionsHumansMiceOligonucleotide Array Sequence AnalysisPolysaccharidesStreptococcal InfectionsStreptococcusStreptococcus agalactiaeStreptococcus pneumoniaeStreptococcus pyogenesVirulence FactorsBacterial ProteinsmaltodextrinPolysaccharidesVirulence Factors

Identifiers

PMID18508271
PMCPMC2975494
OpenAlexW2139969153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.