ReviewWorld journal of gastroenterology2008
Pancreatic function testing: here to stay for the 21st century.
Review in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Diagnostic Accuracy of Fecal Elastase-1 Test for Pancreatic Exocrine Insufficiency: A Systematic Review and Meta-Analysis.United European gastroenterology journal · 2025Pooled it
- American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines.Pancreas · 2014Guideline
- Molecular MRI of Dysregulated Zinc Secretion Detects Pancreatic Ductal Adenocarcinoma and Response to KRASG12D Inhibitor Treatment.Cancer research · 2025Article
- Highly Sensitive Detection of Chymotrypsin Based on Metal Organic Frameworks with Peptides Sensors.Biosensors · 2023Article
- Observational
- Type 1 Diabetes: A Disorder of the Exocrine and Endocrine Pancreas.Journal of cellular immunology · 2023Article
- How Are Imaging Findings Associated with Exocrine Insufficiency in Idiopathic Chronic Pancreatitis?The Indian journal of radiology & imaging · 2022Article
- Assessment of exocrine pancreatic function in children and adolescents with direct and indirect testing.Frontiers in pediatrics · 2022Review
- Imaging of inflammatory disease of the pancreas.The British journal of radiology · 2021Review
- Relationship between Pancreas Exocrine Insufficiency and Cardiac Autonomic Neuropathy in Patients with Type 2 Diabetes Mellitus.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- Pancreatic Enzyme Replacement Therapy in Patients Undergoing First-Line Gemcitabine PlusFrontiers in oncology · 2021Article
- Differential Diagnosis and Management of Diarrhea in Patients with Neuroendocrine Tumors.Journal of clinical medicine · 2020Review
- Exocrine Pancreatic Insufficiency in Type 1 and Type 2 Diabetes.Current diabetes reports · 2020Review
- Review
- Clube Português do Pâncreas Recommendations for Chronic Pancreatitis: Etiology, Natural History, and Diagnosis (Part I).GE Portuguese journal of gastroenterology · 2019Article
- Exocrine pancreatic insufficiency: prevalence, diagnosis, and management.Clinical and experimental gastroenterology · 2019Review
- Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment.Digestive diseases and sciences · 2017Review
- Diagnosing Chronic Pancreatitis.Digestive diseases and sciences · 2017Review
- Potential for Screening for Pancreatic Exocrine Insufficiency Using the Fecal Elastase-1 Test.Digestive diseases and sciences · 2017Review
- Comparing acid steatocrit and faecal elastase estimations for use in M-ANNHEIM staging for pancreatitis.World journal of gastroenterology · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of Chronic Pancreatitis (CP) is based on the detection of abnormal structure or function of the diseased pancreas. The pancreatic function tests more accurately determine the presence of CP than tests of structure, especially for early stage disease. The function tests can be divided into two categories: non-invasive and invasive. The invasive "tube" tests can reliably detect mild, early CP, but are only available at a few referral centers and tend to be poorly tolerated by patients. The non-invasive tests are easy to obtain, but tend to perform poorly in patients with early, mild disease. Therefore, no one test is useful in all clinical situations, and a detailed understanding of the rational, pathophysiologic basis, strengths, and limitations of various tests is needed. This review highlights the role of various pancreatic function tests in the diagnosis of CP including fecal fat analysis, fecal elastase, fecal chymotrypsin, serum trypsin, the secretin stimulation test, the cholecystokinin (CCK) stimulation test, the combined secretin-CCK stimulation test, the intraductal and endoscopic secretin stimulation tests, and the functional magnetic resonance imaging of the pancreas after secretin stimulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.