Evidence map›Paper›PMID 18506804›Full record

ReviewJournal of pharmaceutical sciences2009

Ultrasonic-activated micellar drug delivery for cancer treatment.

Ghaleb A Husseini, William G Pitt

Abstract readReview
In one paragraph

Review in Journal of pharmaceutical sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Ultrasound-Responsive Nanocarriers in Cancer Treatment: A Review.ACS pharmacology & translational science · 2021
    Review
  6. Recent Advances in Nanomicelles Delivery Systems.Nanomaterials (Basel, Switzerland) · 2020
    Review
  7. Ultrasound-based triggered drug delivery to tumors.Drug delivery and translational research · 2018
    Review
  8. Review
  9. Article
  10. Article
  11. A review of low-intensity ultrasound for cancer therapy.Ultrasound in medicine & biology · 2015
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Bioresponsive matrices in drug delivery.Journal of biological engineering · 2010
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ghaleb A HusseiniChemical Engineering Department, American University of Sharjah, Sharjah, United Arab Emirates. ghusseini@aus.edu
William G Pitt

Funding

Controlled Drug Delivery to Colon Tumors Via UltrasoundR01CA098138 · NCI · BRIGHAM YOUNG UNIVERSITY · PI PITT, WILLIAM G · 2004 to 2006
$713k
NCI NIH HHS CA 98138NCI NIH HHS R01 CA098138
6 · The paper itself

Abstract

The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective nanocarrier allows for the delivery of a high concentration of potent medications to targeted tissue while minimizing the side effect of the agent to the rest of the body. Polymeric micelles have been shown to encapsulate therapeutic agents and maintain their structural integrity at lower concentrations. Ultrasound is currently being used in drug delivery as well as diagnostics, and has many advantages that elevate its importance in drug delivery. The technique is noninvasive, thus no surgery is needed; the ultrasonic waves can be easily controlled by advanced electronic technology so that they can be focused on the desired target volume. Additionally, the physics of ultrasound are widely used and well understood; thus ultrasonic application can be tailored towards a particular drug delivery system. In this article, we review the recent progress made in research that utilizes both polymeric micelles and ultrasonic power in drug delivery.

Indexed as

MicellesUltrasonicsAnimalsDrug Delivery SystemsDrug TherapyHumansSurface-Active AgentsMicellesSurface-Active Agents

Identifiers

PMID18506804
PMCPMC2635419

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.