Evidence map›Paper›PMID 18506640›Full record

ReviewClinical reviews in allergy & immunology2008

Diagnosis of cystic fibrosis.

Karen Z Voter, Clement L Ren

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Screening for the Most Common Mutations ofJournal of pediatric genetics · 2020
    Article
  3. Article
  4. Article
  5. Article
  6. Analysis of Cystic Fibrosis in Federation of Bosnia and Herzegovina.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2015
    Article
  7. Article
  8. Article
  9. Atypical cystic fibrosis: identification in the primary care setting.Canadian family physician Medecin de famille canadien · 2012
    Review
  10. Diagnostic tools in Rhinology EAACI position paper.Clinical and translational allergy · 2011
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karen Z VoterDivision of Pediatric Pulmonology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA. Karen_voter@urmc.rochester.edu
Clement L Ren
University of Rochester · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that results in abnormal viscous mucoid secretions in multiple organs and whose main clinical features are pancreatic insufficiency and chronic endobronchial infection. Although it was initially defined and diagnosed based on clinical features and sweat chloride measurement, an in vivo method of assessing CFTR function, the discovery of the CFTR gene in 1989 revealed a broad spectrum of CF phenotypes associated with specific CFTR gene mutations. In this article, we will review the indications for sweat testing, alternative techniques to diagnose CF, and the approach to patients with an ambiguous or indeterminate diagnosis of CF.

Indexed as

Diagnostic Techniques and ProceduresSweatingBronchiectasisChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDiagnosis, DifferentialDNA Mutational AnalysisExocrine Pancreatic InsufficiencyGenes, RecessiveGenetic Predisposition to DiseaseGenotypeHumansMutationChloridesCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID18506640
OpenAlexW2037976878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.