ArticlePlant molecular biology2008
The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses.
Article in Plant molecular biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 55 citations in OpenAlex.
- Coleaf, an image recognition-driven approach facilitates the genome-wide association study with tea leaf morphology.Plant methods · 2026Article
- A dephosphorylation-dependent molecular switch for FT repression mediates flowering in Arabidopsis.Plant communications · 2024Article
- A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis.Nature plants · 2023Article
- Understanding the evolution of miRNA biogenesis machinery in plants with special focus on rice.Functional & integrative genomics · 2023Article
- Chromosome-level genome and high nitrogen stress response of the widespread and ecologically important wetland plantFrontiers in plant science · 2023Article
- CPL2 and CPL3 act redundantly inPlant signaling & behavior · 2022Article
- A Molecular switch for FLOWERING LOCUS C activation determines flowering time in Arabidopsis.The Plant cell · 2022Article
- Mapping the Genetic Regions Responsible for Key Phenology-Related Traits in the European Hazelnut.Frontiers in plant science · 2021Article
- Emerging Roles of RNA-Binding Proteins in Seed Development and Performance.International journal of molecular sciences · 2020Review
- ECERIFERUM11/C-TERMINAL DOMAIN PHOSPHATASE-LIKE2 Affects Secretory Trafficking.Plant physiology · 2019Article
- Gene networks orchestrated by MeGI: a single-factor mechanism underlying sex determination in persimmon.The Plant journal : for cell and molecular biology · 2019Article
- The Arabidopsis RNA Polymerase II Carboxyl Terminal Domain (CTD) Phosphatase-Like1 (CPL1) is a biotic stress susceptibility gene.Scientific reports · 2018Article
- Salt Stress and CTD PHOSPHATASE-LIKE4 Mediate the Switch between Production of Small Nuclear RNAs and mRNAs.The Plant cell · 2017Article
- A protein complex regulates RNA processing of intronic heterochromatin-containing genes inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- KH domain protein RCF3 is a tissue-biased regulator of the plant miRNA biogenesis cofactor HYL1.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity.Cell host & microbe · 2014Article
- Article
- Arabidopsis C-terminal domain phosphatase-like 1 functions in miRNA accumulation and DNA methylation.PloS one · 2013Article
- Article
- Loss of function of Arabidopsis C-terminal domain phosphatase-like1 activates iron deficiency responses at the transcriptional level.Plant physiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 20 genes in the Arabidopsis genome encode proteins similar to phosphatases that act on the carboxyl-terminal domain (CTD) of RNA polymerase II. One of these CTD-phosphatase-like (CPL) proteins, CPL2, dephosphorylates CTD-Ser5-PO4 in an intact RNA polymerase II complex and contains a double-stranded (ds)-RNA-binding motif (DRM). Although the dsRNA-binding activity of CPL2 DRM has not been shown to date, T-DNA insertion mutants that express CPL2 variants lacking either a part of DRM (cpl2-1) or the entire DRM (cpl2-2) exhibited leaf expansion defects, early flowering, low fertility, and increased salt sensitivity. cpl2 mutant plants produced shorter hypocotyls than wild-type plants in the light, but were indistinguishable from wild type in the dark. CPL2 was expressed in shoot and root meristems and vasculatures, expanding rosette leaves, and floral organs suggesting a focal role for growth. Microarray and RT-PCR analyses revealed that basal levels of several auxin-responsive transcripts were reduced in cpl2. On the other hand, the levels of endogenous auxin and its conjugates were similar in wild type and cpl2. Overexpression of ARF5 but not all activator ARF transcription factors restored the auxin-responsive DR5-GUS reporter gene expression and the leaf expansion of cpl2 mutant plants but not early flowering phenotype. These results establish CPL2 as a multifunctional regulator that modulates plant growth, stress, and auxin responses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.