Evidence map›Paper›PMID 18506062›Full record

ArticleILAR journal2008

Old enemies, still with us after all these years.

Charles B Clifford, Julie Watson

Open access · bronzeAbstract read
In one paragraph

Article in ILAR journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Effects of Maternal Fenbendazole on Litter Size, Survival Rate, and Weaning Weight in C57BL/6J Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
  7. Evaluation of In-cage Filter Paper as a Replacement for Sentinel Mice in the Detection of Murine Pathogens.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
  8. Effects of Pelleting, Irradiation, and Autoclaving of Rodent Feed on MPV and MNV Infectivity.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  9. Contaminated Shipping Materials Identified as the Source of Rotaviral Infection of Exported Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2018
    Article
  10. PCR Testing of IVC Filter Tops as a Method for Detecting Murine Pinworms and Fur Mites.Journal of the American Association for Laboratory Animal Science : JAALAS · 2017
    Article
  11. Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected withJournal of the American Association for Laboratory Animal Science : JAALAS · 2017
    Article
  12. Evaluation of Traditional and Contemporary Methods for DetectingJournal of the American Association for Laboratory Animal Science : JAALAS · 2017
    Article
  13. Guidance Regarding Sample Collection and Refinement of Fecal Flotation Exam for the Isolation of Aspiculuris tetraptera.Journal of the American Association for Laboratory Animal Science : JAALAS · 2016
    Article
  14. Article
  15. Characterization of rat pinworm (Syphacia muris) epidemiology as a means to increase detection and elimination.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
  16. Using reduced personal protective equipment in an endemically infected mouse colony.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
  17. Combined evaluation of commonly used techniques, including PCR, for diagnosis of mouse fur mites.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
  18. Incidence rates of spontaneous disease in laboratory mice used at a large biomedical research institution.Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Article
  19. Age-associated variability in susceptibility of Swiss Webster mice to MPV and other excluded murine pathogens.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012
    Article
  20. Variation in airway responsiveness of male C57BL/6 mice from 5 vendors.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Charles B CliffordCharles River Laboratories, 251 Ballardvale Street, Wilmington, MA 01887, USA. charles.clifford@crl.com
Julie Watson
Charles River Laboratories (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although some previously common infections, such as Sendai virus and Mycoplasma pulmonis, have become rare in laboratory rodents in North American research facilities, others continue to plague researchers and those responsible for providing biomedical scientists with animals free of adventitious disease. Long-recognized agents that remain in research facilities in the 21st century include parvoviruses of rats and mice, mouse rotavirus, Theilers murine encephalomyelitis virus (TMEV), mouse hepatitis virus (MHV), and pinworms. The reasons for their persistence vary with the agent. The resilience of parvoviruses, for example, is due to their resistance to inactivation, their prolonged shedding, and difficulties with detection, especially in C57BL/6 mice. Rotavirus also has marked environmental resistance, but periodic reintroduction into facilities, possibly on bags of feed, bedding, or other supplies or equipment, also seems likely. TMEV is characterized by resistance to inactivation, periodic reintroduction, and relatively long shedding periods. Although MHV remains active in the environment at most a few days, currently prevalent strains are shed in massive quantities and likely transmitted by fomites. Pinworm infestations continue because of prolonged infections, inefficient diagnosis, and the survivability of eggs of some species in the environment. For all of these agents, increases in both interinstitutional shipping and the use of immunodeficient or genetically modified rodents of unknown immune status may contribute to the problem, as might incursions by wild or feral rodents. Elimination of these old enemies will require improved detection, strict adherence to protocols designed to limit the spread of infections, and comprehensive eradication programs.

Indexed as

AnimalsEnterobiusMiceMurine hepatitis virusParvovirusRodent DiseasesRotavirusTheilovirus

Identifiers

PMID18506062
PMCPMC7108581
OpenAlexW2152609359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.