ArticleGenetics2008
High DNA sequence diversity in pericentromeric genes of the plant Arabidopsis lyrata.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Structure and sequence evolution in the pennycress (Thlaspi arvense) pangenome.The New phytologist · 2026Article
- The complete reference genome for grapevine (Horticulture research · 2023Article
- Article
- The relationship of recombination rate, genome structure, and patterns of molecular evolution across angiosperms.BMC evolutionary biology · 2015Article
- Evidence for widespread positive and negative selection in coding and conserved noncoding regions of Capsella grandiflora.PLoS genetics · 2014Article
- The relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster.Molecular biology and evolution · 2014Article
- Genome-wide analysis in chicken reveals that local levels of genetic diversity are mainly governed by the rate of recombination.BMC genomics · 2013Article
- Great majority of recombination events in Arabidopsis are gene conversion events.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Review
- Genome-wide survey of pseudogenes in 80 fully re-sequenced Arabidopsis thaliana accessions.PloS one · 2012Article
- Article
- Reduced efficacy of natural selection on codon usage bias in selfing Arabidopsis and Capsella species.Genome biology and evolution · 2011Article
- Construction of a high-density composite map and comparative mapping of segregation distortion regions in barley.Molecular genetics and genomics : MGG · 2010Article
- The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana.Science (New York, N.Y.) · 2010Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differences in neutral diversity at different loci are predicted to arise due to differences in mutation rates and from the "hitchhiking" effects of natural selection. Consistent with hitchhiking models, Drosophila melanogaster chromosome regions with very low recombination have unusually low nucleotide diversity. We compared levels of diversity from five pericentromeric regions with regions of normal recombination in Arabidopsis lyrata, an outcrossing close relative of the highly selfing A. thaliana. In contrast with the accepted theoretical prediction, and the pattern in Drosophila, we found generally high diversity in pericentromeric genes, which is consistent with the observation in A. thaliana. Our data rule out balancing selection in the pericentromeric regions, suggesting that hitchhiking is more strongly reducing diversity in the chromosome arms than the pericentromere regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.