ArticleDevelopment genes and evolution2008
Developmental expression of homeobox genes in the ctenophore Mnemiopsis leidyi.
Article in Development genes and evolution, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 72 citations in OpenAlex.
- An Integrated Canonical and Non-Canonical Wnt Signaling Network Controls Early Anterior-Posterior Axis Formation in Sea Urchin Embryos.Journal of developmental biology · 2025Review
- Morphological and dietary changes encoded in the genome ofNAR genomics and bioinformatics · 2024Article
- The ctenophore Mnemiopsis leidyi deploys a rapid injury response dating back to the last common animal ancestor.Communications biology · 2024Article
- Coevolution of the Tlx homeobox gene with medusa development (Cnidaria: Medusozoa).Communications biology · 2023Article
- Independent Innexin Radiation Shaped Signaling in Ctenophores.Molecular biology and evolution · 2023Article
- Mass spectrometry of short peptides reveals common features of metazoan peptidergic neurons.Nature ecology & evolution · 2022Article
- Multigenerational laboratory culture of pelagic ctenophores and CRISPR-Cas9 genome editing in the lobate Mnemiopsis leidyi.Nature protocols · 2022Review
- The Mnemiopsis Genome Project Portal: integrating new gene expression resources and improving data visualization.Database : the journal of biological databases and curation · 2020Article
- Expression of NK genes that are not part of the NK cluster in the onychophoran Euperipatoides rowelli (Peripatopsidae).BMC developmental biology · 2019Article
- Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning inCommunications biology · 2019Article
- Integrating Embryonic Development and Evolutionary History to Characterize Tentacle-Specific Cell Types in a Ctenophore.Molecular biology and evolution · 2018Article
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- A new paradigm for animal symmetry.Interface focus · 2015Review
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- The genome of the ctenophore Mnemiopsis leidyi and its implications for cell type evolution.Science (New York, N.Y.) · 2013Article
- Evidence for involvement of Wnt signalling in body polarities, cell proliferation, and the neuro-sensory system in an adult ctenophore.PloS one · 2013Article
- A diploblastic radiate animal at the dawn of cambrian diversification with a simple body plan: distinct from Cnidaria?PloS one · 2013Article
- Lim homeobox genes in the Ctenophore Mnemiopsis leidyi: the evolution of neural cell type specification.EvoDevo · 2012Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Homeobox genes are a large family of genes that encode helix-turn-helix transcription factors that play fundamental roles in such developmental processes including body axis formation and cell specification. They have been found in a wide variety of organisms, from fungi to plants and animals, with some classes being specific to the Metazoa. While it was once thought that organismal complexity was tied to gene complexity, sequencing of genomes from a cnidarian, poriferan, and placozoan have shown no clear correlation. However, little attention has been paid to ctenophores, another early branching taxon. Ctenophores are mostly pelagic marine animals, with complex morphological features, so understanding the gene content and expression of this nonbilaterian phylum is of key interest to evolutionary biology. Expression information from developmental genes in ctenophores is sparse. In this study, we isolated seven homeobox genes from the ctenophore Mnemiopsis leidyi and examined their expression through development. Phylogenetic analyses of these genes placed four in the ANTP class and three in the PRD class. These are the first reported full-length PRD class genes, although our analyses could not place them into specific families. We have found that most of these homeobox genes begin expression at gastrulation, and their expression patterns suggest a possible role in patterning of the tentacle apparati and pharynx.
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