Evidence map›Paper›PMID 18502978›Full record

ReviewProtein science : a publication of the Protein Society2008

Kinetic barriers and the role of topology in protein and RNA folding.

Tobin R Sosnick

Abstract readReview
In one paragraph

Review in Protein science : a publication of the Protein Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Protein unfolding rates correlate as strongly as folding rates with native structure.Protein science : a publication of the Protein Society · 2015
    Article
  8. Atomic-level description of ubiquitin folding.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Modeling large regions in proteins: applications to loops, termini, and folding.Protein science : a publication of the Protein Society · 2012
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Physics-based de novo prediction of RNA 3D structures.The journal of physical chemistry. B · 2011
    Article
  19. The folding of single domain proteins--have we reached a consensus?Current opinion in structural biology · 2011
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tobin R SosnickUniversity of Chicago, 929 East 57th Street, GCIS W107E, Chicago, IL 60637, USA. trsosnic@uchicago.edu

Funding

Kinetic studies of protein foldingR01GM055694 · NIGMS · UNIVERSITY OF CHICAGO · PI SOSNICK, TOBIN R · 2001 to 2022
$7.6M
KINETIC/THERMODYNAMIC/STRUCTURAL STUDIES OF RNA FOLDINGR01GM057880 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 1998 to 2011
$2.6M
Kinetic/Thermodynamic/Structural Studies of RNA FoldingR56GM057880 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2007 to 2007
$307k
FOLDING OF AN ALPHA-HELICAL COILED COILR29GM055694 · NIGMS · UNIVERSITY OF CHICAGO · PI SOSNICK, TOBIN R · 1996 to 2000
$107k
NIGMS NIH HHS GM55694NIGMS NIH HHS GM57880NIGMS NIH HHS R01 GM055694NIGMS NIH HHS R01 GM057880NIGMS NIH HHS R29 GM055694NIGMS NIH HHS R56 GM057880
6 · The paper itself

Abstract

This review compares the folding behavior of proteins and RNAs. Topics covered include the role of topology in the determination of folding rates, major folding events including collapse, properties of denatured states, pathway heterogeneity, and the influence of the mode of initiation on the folding pathway.

Indexed as

Nucleic Acid ConformationProtein FoldingAnimalsHumansModels, MolecularNucleic Acid DenaturationProtein DenaturationProteinsProtein Structure, SecondaryRNAProteinsRNA

Identifiers

PMID18502978
PMCPMC2492822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.