ArticleBMC genomics2008
Gene discovery in an invasive tephritid model pest species, the Mediterranean fruit fly, Ceratitis capitata.
Article in BMC genomics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 95 citations in OpenAlex.
- Overwintering Capacity of the Mediterranean Fruit Fly in the Dalmatia Region of Croatia.Insects · 2025Article
- Temperature and Host Fruit During Immature Development Shape Adult Life History Traits of DifferentInsects · 2025Article
- Latitudinal variation in survival and immature development of Ceratitis capitata populations reared in two key overwintering hosts.Scientific reports · 2024Article
- A two-level staging system for the embryonic morphogenesis of the Mediterranean fruit fly (medfly) Ceratitis capitata.PloS one · 2024Article
- Learning algorithms estimate pose and detect motor anomalies in flies exposed to minimal doses of a toxicant.iScience · 2023Article
- Next-generation genetic sexing strain establishment in the agricultural pest Ceratitis capitata.Scientific reports · 2023Article
- In toto light sheet fluorescence microscopy live imaging datasets of Ceratitis capitata embryonic development.Scientific data · 2022Article
- Review
- Transcriptome analysis of Anastrepha fraterculus sp. 1 males, females, and embryos: insights into development, courtship, and reproduction.BMC genetics · 2020Article
- Female-to-male sex conversion in Ceratitis capitata by CRISPR/Cas9 HDR-induced point mutations in the sex determination gene transformer-2.Scientific reports · 2020Article
- A First Glimpse of the Mexican Fruit FlyInternational journal of molecular sciences · 2020Article
- Transcriptome Analysis of the Oriental Fruit FlyInsects · 2020Article
- Identification of sex determination genes and their evolution in Phlebotominae sand flies (Diptera, Nematocera).BMC genomics · 2019Article
- Two of the three Transformer-2 genes are required for ovarian development in Aedes albopictus.Insect biochemistry and molecular biology · 2019Article
- Instar- and host-associated differentiation of bacterial communities in the Mediterranean fruit fly Ceratitis capitata.PloS one · 2018Article
- Current source density mapping of antennal sensory selectivity reveals conserved olfactory systems between tephritids and Drosophila.Scientific reports · 2017Article
- Article
- The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species.Genome biology · 2016Article
- Identification and preliminary characterization of chemosensory perception-associated proteins in the melon fly Bactrocera cucurbitae using RNA-seq.Scientific reports · 2016Article
- Olive fly transcriptomics analysis implicates energy metabolism genes in spinosad resistance.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe medfly, Ceratitis capitata, is a highly invasive agricultural pest that has become a model insect for the development of biological control programs. Despite research into the behavior and classical and population genetics of this organism, the quantity of sequence data available is limited. We have utilized an expressed sequence tag (EST) approach to obtain detailed information on transcriptome signatures that relate to a variety of physiological systems in the medfly; this information emphasizes on reproduction, sex determination, and chemosensory perception, since the study was based on normalized cDNA libraries from embryos and adult heads.
resultsA total of 21,253 high-quality ESTs were obtained from the embryo and head libraries. Clustering analyses performed separately for each library resulted in 5201 embryo and 6684 head transcripts. Considering an estimated 19% overlap in the transcriptomes of the two libraries, they represent about 9614 unique transcripts involved in a wide range of biological processes and molecular functions. Of particular interest are the sequences that share homology with Drosophila genes involved in sex determination, olfaction, and reproductive behavior. The medfly transformer2 (tra2) homolog was identified among the embryonic sequences, and its genomic organization and expression were characterized.
conclusionThe sequences obtained in this study represent the first major dataset of expressed genes in a tephritid species of agricultural importance. This resource provides essential information to support the investigation of numerous questions regarding the biology of the medfly and other related species and also constitutes an invaluable tool for the annotation of complete genome sequences. Our study has revealed intriguing findings regarding the transcript regulation of tra2 and other sex determination genes, as well as insights into the comparative genomics of genes implicated in chemosensory reception and reproduction.
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