Evidence map›Paper›PMID 18500499›Full record

ArticleJournal of neurology2008

Rehabilitation in primary and metastatic brain tumours: impact of functional outcomes on survival.

V Tang, M Rathbone, J Park Dorsay, S Jiang, D Harvey

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Optimizing post-acute care inpatient rehabilitation for patients with brain metastasis: A systematic review of functional outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
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  4. Multidisciplinary rehabilitation after primary brain tumour treatment.The Cochrane database of systematic reviews · 2015
    Pooled it
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  13. Precision Surgery for Glioblastomas.Journal of personalized medicine · 2025
    Review
  14. Corticosteroids in lung cancer.Frontiers in drug safety and regulation · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

V TangDivision of Neurology, McMaster University, Hamilton, Canada.
M Rathbone
J Park Dorsay
S Jiang
D Harvey
McMaster University · CAHamilton Health Sciences · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with brain tumours have major disabilities and guarded prognosis but may benefit from inpatient rehabilitation.The objectives were to compare functional outcomes inpatients with glioblastoma multiforme(GBM), brain metastases and other brain tumours, and to determine predictors of survival.

methodsDemographic, clinical,functional, and survival data were collected for 63 patients.Kaplan-Meier and Cox regression were used for survival analyses.

resultsFunctional Independence Measure(FIM ) scores improved from admission to discharge for patients with GBM, brain metastases and other tumours. Estimated median survival was 141 days for brain metastases, 214 days for GBM and 439 days for other tumours. Low admission dexamethasone dose and high FIM gain predicted better survival in GBM. For brain metastases, high FIM gain, low dexamethasone dose and no organ metastases were positive prognostic factors.

conclusionsPatients with primary and metastatic brain tumours achieved functional gains after rehabilitation. High functional improvement is a significant predictor of longer survival in brain metastases and GBM. This study has implications for rehabilitation in the post-acute management of patients who have disabilities due to brain tumours.

Indexed as

Activities of Daily LivingAgedAntineoplastic Agents, HormonalBrainBrain NeoplasmsDexamethasoneFemaleGlioblastomaHumansLength of StayMaleMiddle AgedNeoplasm MetastasisOutcome Assessment, Health CarePrognosisQuality of LifeAntineoplastic Agents, HormonalDexamethasone

Identifiers

PMID18500499
OpenAlexW1543461451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.