Evidence map›Paper›PMID 18500424›Full record

ArticleIntensive care medicine2008

Non-invasive ventilation as primary ventilatory support for infants with severe bronchiolitis.

Etienne Javouhey, Audrey Barats, Nathalie Richard, Didier Stamm, Daniel Floret

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06053684 (Comparison of Conventional Non-Invasive Ventilation and Neurally-Adjusted Ventilatory Assistance), which is not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06053684 narecruitingnot on this mapstarted 2023, after this paper: background citation

Comparison of Conventional Non-Invasive Ventilation and Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Ventilation for the Treatment of Bronchiolitis

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2027Enrolled130ConditionsBronchiolitisArmsStandard Non-Invasive Mechanical Servo Ventilation, Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024
    Review
  8. Acute Viral Bronchiolitis: A Narrative Review.Journal of pediatric intensive care · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Clinico-virological Profile, Intensive Care Needs, and Outcome of Infants with Acute Viral Bronchiolitis: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Noninvasive Ventilation and High-Flow NasalSultan Qaboos University medical journal · 2018
    Review
  18. Article
  19. Article
  20. Effectiveness of flow inflating device in providing Continuous Positive Airway Pressure for critically ill children in limited-resource settings: A prospective observational study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Etienne JavouheyService de Réanimation Pédiatrique Hôpital Femme Mère Enfant, Groupement Hospitalier Est, 59 Boulevard Pinel, Hospices Civils de Lyon, Université Lyon 1, 69677, Bron Cedex, France. etienne.javouhey@chu-lyon.fr
Audrey Barats
Nathalie Richard
Didier Stamm
Daniel Floret
Université Claude Bernard Lyon 1 · FRHôpital d'Hautepierre · FRHôpital Femme Mère Enfant · FRLyon College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report our experience of non-invasive ventilation (NIV) as primary ventilatory support strategy in infants admitted for severe bronchiolitis. DESIGN AND

settingRetrospective study in a paediatric intensive care unit of an university hospital. PATIENTS: Infants aged less than 12 months, admitted for bronchiolitis during 2003-2004 and 2004-2005 winter epidemics.

interventionNIV was used as the primary ventilatory support during the second winter (NIV period), whereas invasive ventilation (IV) was the only support employed during the first winter (IV period). NIV consisted in either continuous positive airway pressure (CPAP from 5 to 10 cmH(2)O) or bilevel positive airway pressure (inspiratory pressure from 12 to 18 cmH(2)O) with a nasal mask.

resultsDuring the IV period, 53 infants were included, compared to 27 during the NIV period. The two groups did not differ in age or in number of premature births. Children in NIV group had less apnoea on admission. The intubation rate was reduced during NIV period (p < 0.001). No children had ventilator-associated pneumonia (VAP) during NIV period compared to nine during IV period (p < 0.05). In the NIV group, 10 infants (37%) required supplemental oxygen for more than 8 days compared to 33 children (65%) in IV group (p < 0.05). The length of hospital stay and the duration of ventilation were similar.

conclusionsIn this retrospective study, the use of NIV decreased the rate of ventilator associated pneumonia and reduced the duration of oxygen requirement without prolonging the hospital stay.

Indexed as

BronchiolitisFemaleHumansInfantInfant, NewbornIntensive Care Units, PediatricLength of StayMalePneumonia, Ventilator-AssociatedPositive-Pressure RespirationRetrospective Studies

Identifiers

PMID18500424
OpenAlexW2129328888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.