ArticleNeuron2008
Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.
Article in Neuron, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
84 citing papers in PubMed, 139 citations in OpenAlex.
- Cholinergic Waves Have a Modest Influence on the Transcriptome of Retinal Ganglion Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Transformation of Motion Pattern Selectivity from Retina to Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- The Interplay between Neurotransmitters and Calcium Dynamics in Retinal Synapses during Development, Health, and Disease.International journal of molecular sciences · 2024Review
- Acetylcholine Promotes Directionally Biased Glutamatergic Retinal Waves.bioRxiv : the preprint server for biology · 2023Article
- Article
- Azimuthal invariance to looming stimuli in the Drosophila giant fiber escape circuit.The Journal of experimental biology · 2023Article
- Roles of visually evoked and spontaneous activity in the development of retinal direction selectivity maps.Trends in neurosciences · 2022Review
- Development of Functional Properties in the Early Visual System: New Appreciations of the Roles of Lateral Geniculate Nucleus.Current topics in behavioral neurosciences · 2022Review
- Development of the vertebrate retinal direction-selective circuit.Developmental biology · 2021Review
- Visual Disfunction due to the Selective Effect of Glutamate Agonists on Retinal Cells.International journal of molecular sciences · 2021Article
- Lack of Evidence for Stereotypical Direction Columns in the Mouse Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Global Motion Processing by Populations of Direction-Selective Retinal Ganglion Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Early Visual Motion Experience Improves Retinal Encoding of Motion Directions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Early visual motion experience shapes the gap junction connections among direction selective ganglion cells.PLoS biology · 2020Article
- Expression of transcription factors divides retinal ganglion cells into distinct classes.The Journal of comparative neurology · 2019Article
- Pathway-Specific Asymmetries between ON and OFF Visual Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells.Neuron · 2018Article
- Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Large scale matching of function to the genetic identity of retinal ganglion cells.Scientific reports · 2017Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Direction selectivity in the retina requires the asymmetric wiring of inhibitory inputs onto four subtypes of On-Off direction-selective ganglion cells (DSGCs), each preferring motion in one of four cardinal directions. The primary model for the development of direction selectivity is that patterned activity plays an instructive role. Here, we use a unique, large-scale multielectrode array to demonstrate that DSGCs are present at eye opening, in mice that have been reared in darkness and in mice that lack cholinergic retinal waves. These data suggest that direction selectivity in the retina is established largely independent of patterned activity and is therefore likely to emerge as a result of complex molecular interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.